Catalog No.
PMN02401
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse JAML (Gln32-Asp256).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Dendritic cell-specific protein CREA7-1, Adhesion molecule interacting with CXADR antigen 1, Junctional adhesion molecule-like, AMICA1, JAML
Purification
Purified by antigen affinity column.
Accession
Q80UL9
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeted activation of junctional adhesion molecule-like protein+ CD8+ T cells enhances immunotherapy in hepatocellular carcinoma., PMID:40353078
JAML immunotherapy targets recently activated tumor-infiltrating CD8+ T cells., PMID:36701231
JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy., PMID:34427588
Infliximab treatment in pathology-confirmed neurosarcoidosis., PMID:32718952
Silencing of junctional adhesion molecule-like protein attenuates atherogenesis and enhances plaque stability in ApoE-/- mice., PMID:31101724
Junctional adhesion molecules mediate transendothelial migration of dendritic cell vaccine in cancer immunotherapy., PMID:30055289
Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation., PMID:24621992
cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for γδ T cells., PMID:21629689
Molecular insights into γδ T cell costimulation by an anti-JAML antibody., PMID:21220118
Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils., PMID:15800062
Ultrastructural evidence for direct projections from the pontine micturition center to glycine-immunoreactive neurons in the sacral dorsal gray commissure in the cat., PMID:11135240