Catalog No.
PMK22901
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse TIMD4/TIM-4 (Glu25-Arg133).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TIMD4, T-cell immunoglobulin mucin receptor 4, TIM-4, TIMD-4, T-cell membrane protein 4, TIM4, T-cell immunoglobulin and mucin domain-containing protein 4
Purification
Purified by antigen affinity column.
Accession
Q6U7R4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
In Situ Proefferocytosis Microspheres as Macrophage Polarity Converters Accelerate Osteoarthritis Treatment., PMID:39780612
Proteogenomic links to human metabolic diseases., PMID:36823471
TIM-4 in macrophages contributes to nasal polyp formation through the TGF-β1-mediated epithelial to mesenchymal transition in nasal epithelial cells., PMID:35990621
Platelet-derived extracellular vesicles are increased in sera of Alzheimer's disease patients, as revealed by Tim4-based assays., PMID:33345458
Overexpression of Nuclear Enriched Autosomal Transcript 1 Facilitates Cell Proliferation, Migration Invasion, and Suppresses Apoptosis in Endometrial Cancer by Targeting MicroRNA-202-3p/T Cell Immunoglobulin and Mucin Domain 4 Axis., PMID:32882142
Characterization of Subpopulations of Chicken Mononuclear Phagocytes That Express TIM4 and CSF1R., PMID:30626692
Differential Interaction of Platelet-Derived Extracellular Vesicles With Circulating Immune Cells: Roles of TAM Receptors, CD11b, and Phosphatidylserine., PMID:30619243
Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells., PMID:28740388
TIM-1 Promotes Hepatitis C Virus Cell Attachment and Infection., PMID:27807228
Blocking monoclonal antibodies of TIM proteins as orchestrators of anti-tumor immune response., PMID:25517298
Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine., PMID:24286866
Cockroach allergen Bla g 7 promotes TIM4 expression in dendritic cells leading to Th2 polarization., PMID:24204099
The T-cell immunoglobulin and mucin domain (Tim) gene family in asthma, allergy, and autoimmunity., PMID:23406933
A new development of FG-CC' siRNA blocking interaction of Tim-1 and Tim-4 can enhance DC vaccine against gastric cancer ., PMID:22709877
Interactions of human T cell immunoglobin mucins with apoptotic cells., PMID:22282238
Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds., PMID:18083575
TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells., PMID:18082433
Identification of Tim4 as a phosphatidylserine receptor., PMID:17960135
Staphylococcal enterotoxin B increases TIM4 expression in human dendritic cells that drives naïve CD4 T cells to differentiate into Th2 cells., PMID:17439824
For research use only. Not for human or drug use.
