Catalog No.
PME22701
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse IFNGR2 (Tyr289-Pro332).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
IFN-gamma receptor 2, Interferon gamma receptor beta-chain, Interferon gamma transducer 1, IFN-gamma-R-beta, AF-1, IFN-gamma-R2, IFNGT1, Interferon gamma receptor accessory factor 1, Interferon gamma receptor 2, IFNGR2
Purification
Purified by antigen affinity column.
Accession
Q63953
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
CircIFNGR2 enhances proliferation and migration of CRC and induces cetuximab resistance by indirectly targeting KRAS via sponging to MiR-30b., PMID:36639711
IFN-γ promotes the development of systemic lupus erythematosus through the IFNGR1/2-PSTAT1-TBX21 signaling axis., PMID:36398225
Classification of invasive bloodstream infections and Plasmodium falciparum malaria using autoantibodies as biomarkers., PMID:33273605
PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma., PMID:32358509
Genome-Wide CRISPR Screen Reveals Cancer Cell Resistance to NK Cells Induced by NK-Derived IFN-γ., PMID:31921143
IFN-γ inhibits 5-HT-induced melanin biosynthesis via downregulation of 5-HT receptors in vivo/in vitro., PMID:31519333
T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells., PMID:31076359
Selective targeting of interferon γ to stromal fibroblasts and pericytes as a novel therapeutic approach to inhibit angiogenesis and tumor growth., PMID:22933708
Monocyte-derived CD40 expression is regulated by interferon-γ/interferon-γ receptor-1 pathway when acting as a bridge during their interaction with T cells and allogeneic endothelial cells., PMID:22564607
Bovine IFNGR2, IL12RB1, IL12RB2, and IL23R polymorphisms and MAP infection status., PMID:21597988
FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin., PMID:17239631
Genetic polymorphism of interferon-gamma, interferon-gamma receptor, and interferon regulatory factor-1 genes in patients with hepatitis B virus infection., PMID:16944293
Deferoxamine enhances anti-proliferative effect of interferon-gamma against hepatocellular carcinoma cells., PMID:16837131
Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor., PMID:16135815
Phorbol myristate acetate and Bryostatin 1 rescue IFN-gamma inducibility of MHC class II molecules in LS1034 colorectal carcinoma cell line., PMID:12787470
Mouse oocytes and preimplantation embryos bear the two sub-units of interferon-gamma receptor., PMID:11599043
Sézary T-cell activating factor is a Chlamydia pneumoniae-associated protein., PMID:10548583
Nonpathogenic common variants of IFNGR1 and IFNGR2 in association with total serum IgE levels., PMID:10491309
Sézary syndrome T-cell clones display T-helper 2 cytokines and express the accessory factor-1 (interferon-gamma receptor beta-chain)., PMID:8695857