Catalog No.
PHJ68301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human LYAR (Gly307-Lys379).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Cell growth-regulating nucleolar protein, LYAR
Purification
Purified by antigen affinity column.
Accession
Q9NX58
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A Comprehensive Analysis of LYAR in Colorectal Cancer: Prognostic Marker and Therapeutic Target., PMID:39159060
The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers., PMID:36614221
Distinct gene expression by expanded clones of quiescent memory CD4+ T cells harboring intact latent HIV-1 proviruses., PMID:36070690
LYAR promotes the proliferation of non-small cell lung cancer and is associated with poor prognosis., PMID:34890041
Analysis of the role of Ly-1 antibody reactive in different cancer types., PMID:34696677
LINC00355 promoted the progression of lung squamous cell carcinoma through regulating the miR-466/LYAR axis., PMID:33111744
Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia., PMID:31300855
Formation of mammalian preribosomes proceeds from intermediate to composed state during ribosome maturation., PMID:31076509
An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production., PMID:28851297
A Genetic Variant Ameliorates β-Thalassemia Severity by Epigenetic-Mediated Elevation of Human Fetal Hemoglobin Expression., PMID:28669403
Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels., PMID:26897028
LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression., PMID:26413750
Lyar Is a New Ligand for Retinal Pigment Epithelial Phagocytosis., PMID:25735755
Human fetal globin gene expression is regulated by LYAR., PMID:25092918
Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA., PMID:24495227
Expression and function of the testis-predominant protein LYAR in mice., PMID:23212345
Mutations in Lyar and p53 are synergistically lethal in female mice., PMID:22815056
Ly-1 antibody reactive clone is an important nucleolar protein for control of self-renewal and differentiation in embryonic stem cells., PMID:19489080
Antigen-receptor cross-linking induces peritoneal B-cell apoptosis in normal but not autoimmunity-prone mice., PMID:7922322
LYAR, a novel nucleolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation., PMID:8491376
For research use only. Not for human or drug use.
