Catalog No.
PHN34001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PNPLA3 (Met1-Lys252).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3, iPLA2-epsilon, C22orf20, Lysophosphatidic acid acyltransferase, Acylglycerol transacylase, Calcium-independent phospholipase A2-epsilon, Patatin-like phospholipase domain-containing protein 3, ADPN, Adiponutrin, PNPLA3
Purification
Purified by antigen affinity column.
Accession
Q9NST1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The effect of dulaglutide on glycated hemoglobin is associated with PNPLA3 Ι148Μ gene polymorphism in patients with type 2 diabetes mellitus., PMID:39179734
Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans., PMID:35833455
Clozapine Worsens Glucose Intolerance, Nonalcoholic Fatty Liver Disease, Kidney Damage, and Retinal Injury and Increases Renal Reactive Oxygen Species Production and Chromium Loss in Obese Mice., PMID:34206460
Association between positivity of serum autoantibodies and liver disease severity in patients with biopsy-proven NAFLD., PMID:33250371
The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C., PMID:29258449
Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease., PMID:28902428
Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study., PMID:28660493
Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation., PMID:28433418
Impact of IL28B and PNPLA3 polymorphisms on treatment outcomes in patients infected with genotype 6 hepatitis C virus., PMID:25639146
For research use only. Not for human or drug use.
