Catalog No.
PHN33801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ANO2 (Arg188-Ala365).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
C12orf3, ANO2, Transmembrane protein 16B, TMEM16B, Anoctamin-2
Purification
Purified by antigen affinity column.
Accession
Q9NQ90
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Antibody reactivity against EBNA1 and GlialCAM differentiates multiple sclerosis patients from healthy controls., PMID:40063790
In-depth analysis of serum antibodies against Epstein-Barr virus lifecycle proteins, and EBNA1, ANO2, GlialCAM and CRYAB peptides in patients with multiple sclerosis., PMID:39742283
Enhanced and cross-reactive in vitro memory B cell response against Epstein-Barr virus nuclear antigen 1 in multiple sclerosis., PMID:39257578
ANO2 Genetic Variants and Anti-VEGF Treatment Response in Neovascular AMD: A Pharmacogenetic Substudy of VIEW 1 and VIEW 2., PMID:38980270
Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal damage., PMID:37802637
Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling., PMID:32517157
Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk., PMID:31375628
Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test., PMID:31328572
[Screening of familial primary biliary cholangitis and research on low-frequency mutations by whole-exome sequencing]., PMID:29996209
TMEM16A inhibition impedes capacitation and acquisition of hyperactivated motility in guinea pig sperm., PMID:29600587
Single Ca(2+)-activated Cl(-) channel currents recorded from toad olfactory cilia., PMID:27113933
Anoctamin 2 identified as an autoimmune target in multiple sclerosis., PMID:26862169
Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle., PMID:23997176
Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons., PMID:23874937
Targeted expression of anoctamin calcium-activated chloride channels in rod photoreceptor terminals of the rodent retina., PMID:23557741
Heteroligation of a mouse monoclonal IgE antibody (La2) with small molecules, analysed by computer-aided automated docking., PMID:8649435
Modeling the antigen combining site of an anti-dinitrophenyl antibody, ANO2., PMID:1303765
Binding and mobility of anti-dinitrophenyl monoclonal antibodies on fluid-like, Langmuir-Blodgett phospholipid monolayers containing dinitrophenyl-conjugated phospholipids., PMID:2036437
Slow rotational mobilities of antibodies and lipids associated with substrate-supported phospholipid monolayers as measured by polarized fluorescence photobleaching recovery., PMID:2207246
For research use only. Not for human or drug use.
