Catalog No.
PHN33401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SPACA1 (Glu78-Thr201).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Sperm acrosomal membrane-associated protein 32, SAMP32, Sperm acrosome membrane-associated protein 1, SPACA1
Purification
Purified by antigen affinity column.
Accession
Q9HBV2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Bioinformatic prediction of the structure and characteristics of human sperm acrosome membrane-associated protein 1 (hSAMP32) and evaluation of its antifertility function in vivo., PMID:33220718
Cleavage of SPACA1 regulates assembly of sperm-egg membrane fusion machinery in mature spermatozoa†., PMID:31836887
Proteomic Analysis of Dpy19l2-Deficient Human Globozoospermia Reveals Multiple Molecular Defects., PMID:31424156
Changes in the distribution and molecular mass of boar sperm acrosome-associated 1 proteins during the acrosome reaction; their validity as indicators for occurrence of the true acrosome reaction., PMID:27449406
Individual differences in the distribution of sperm acrosome-associated 1 proteins among male patients of infertile couples; their possible impact on outcomes of conventional in vitro fertilization., PMID:27185107
A Novel Testis-Specific Gene, Ccdc136, Is Required for Acrosome Formation and Fertilization in Mice., PMID:27076447
Acrosome markers of human sperm., PMID:26748928
Discovery of human posterior head 20 (hPH20) and homo sapiens sperm acrosome associated 1 (hSPACA1) immunocontraceptive epitopes and their effects on fertility in male and female mice., PMID:25209425
Case report of apoptosis in testis of four AZFc-deleted patients: increased DNA fragmentation during meiosis, but decreased apoptotic markers in post-meiotic germ cells., PMID:22508792
The equatorial subsegment in mammalian spermatozoa is enriched in tyrosine phosphorylated proteins., PMID:18448843
Immunogenicity of a multi-component recombinant human acrosomal protein vaccine in female Macaca fascicularis., PMID:17643494
Identification of sperm immunoreactive antigens for immunocontraceptive purposes: a review., PMID:15035665
SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa., PMID:12606493
SAMP32, a testis-specific, isoantigenic sperm acrosomal membrane-associated protein., PMID:11870081