Catalog No.
PHN29801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CELF1 (Lys17-Asp187).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CELF-1, CUGBP1, CUGBP Elav-like family member 1, Deadenylation factor CUG-BP, Embryo deadenylation element-binding protein homolog, EDEN-BP homolog, CELF1, RNA-binding protein BRUNOL-2, 50 kDa nuclear polyadenylated RNA-binding protein, CUG triplet repeat RNA-binding protein 1, BRUNOL2, CUGBP, NAB50, CUG-BP- and ETR-3-like factor 1, Bruno-like protein 2, CUG-BP1
Purification
Purified by antigen affinity column.
Accession
Q92879
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation., PMID:34471108
The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development., PMID:32594240
CELF1 preferentially binds to exon-intron boundary and regulates alternative splicing in HeLa cells., PMID:28733224
The Expression of CUGBP1 After Spinal Cord Injury in Rats., PMID:26283512
Altered CELF1 binding to target transcripts in malignant T cells., PMID:26249002
Alternative splicing dysregulation secondary to skeletal muscle regeneration., PMID:21400563
Analysis of CUGBP1 targets identifies GU-repeat sequences that mediate rapid mRNA decay., PMID:20547756
Expansion of CUG RNA repeats causes stress and inhibition of translation in myotonic dystrophy 1 (DM1) cells., PMID:20479119
Localized co-transcriptional recruitment of the multifunctional RNA-binding protein CELF1 by lampbrush chromosome transcription units., PMID:18095176
Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR., PMID:12022233
In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts., PMID:11433021
Elf-1 is a transcriptional regulator of the Tie2 gene during vascular development., PMID:11157678