Catalog No.
PHK27001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human KNL1 (Ser2131-Asp2337).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Blinkin, CT29, Kinetochore-null protein 1, Cancer/testis antigen 29, Bub-linking kinetochore protein, Protein CASC5, Protein D40/AF15q14, ALL1-fused gene from chromosome 15q14 protein, Kinetochore scaffold 1, CASC5, KNL1, Cancer susceptibility candidate gene 5 protein, KIAA1570, AF15q14
Purification
Purified by antigen affinity column.
Accession
Q8NG31
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Differential anti-viral response to respiratory syncytial virus A in preterm and term infants., PMID:38447274
KNL1 and NDC80 represent new universal markers for the detection of functional centromeres in plants., PMID:38403686
The Loss-Function of KNL1 Causes Oligospermia and Asthenospermia in Mice by Affecting the Assembly and Separation of the Spindle through Flow Cytometry and Immunofluorescence., PMID:36904774
Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins., PMID:29764992
A quantitative description of Ndc80 complex linkage to human kinetochores., PMID:26345214
Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T., PMID:25660545
Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction., PMID:22331848
Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore., PMID:21353556
CENP-C is a structural platform for kinetochore assembly., PMID:21353555
The protein encoded by cancer/testis gene D40/AF15q14 is localized in spermatocytes, acrosomes of spermatids and ejaculated spermatozoa., PMID:15579588
Isolation of the peri-acrosomal plasma membrane protein D40 enriched fraction from guinea pig spermatozoa using a monoclonal antibody., PMID:11857474
For research use only. Not for human or drug use.
