Catalog No.
PHD77501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TMOD1 (Gly160-Gly349).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
E-Tmod, Erythrocyte tropomodulin, D9S57E, TMOD, Tropomodulin-1, TMOD1
Purification
Purified by antigen affinity column.
Accession
P28289
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin., PMID:27139341
Disruption in the tropomodulin1 (Tmod1) gene compromises cardiomyocyte development in murine embryonic stem cells by arresting myofibril maturation., PMID:15950601
The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes., PMID:12975349
Vertebrate tropomyosin: distribution, properties and function., PMID:11563548
Leiomodin and tropomodulin in smooth muscle., PMID:11350761
The N-terminal end of nebulin interacts with tropomodulin at the pointed ends of the thin filaments., PMID:11016930
Tropomodulin-binding site mapped to residues 7-14 at the N-terminal heptad repeats of tropomyosin isoform 5., PMID:10871039
N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin., PMID:8886980
The differential adhesion forces of anterior cruciate and medial collateral ligament fibroblasts: effects of tropomodulin, talin, vinculin, and alpha-actinin., PMID:8799175
Tropomodulin in rat cardiac muscle. Localization of protein is independent of messenger RNA distribution during myofibrillar development., PMID:8033336
Identification and characterization of tropomodulin and tropomyosin in the adult rat lens., PMID:7929641
Tropomodulin is highly concentrated at the postsynaptic domain of human and rat neuromuscular junctions., PMID:8262158
Tropomodulin is associated with the free (pointed) ends of the thin filaments in rat skeletal muscle., PMID:8421055
Nature of 64 kDa eye muscle and thyroid membrane proteins and their significance in thyroid-associated ophthalmopathy--an hypothesis., PMID:8180320