Catalog No.
YMD72501
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Asp49-Cys323
Predicted molecular weight
32.46 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26952
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL-3R subunit alpha, IL-3 receptor subunit alpha, CD123, Interleukin-3 receptor subunit alpha, IL3R, IL-3R-alpha, IL3RA, IL-3RA
Case Report: Flow cytometric differential diagnosis of a peripheral T-cell lymphoma, NOS with complete loss of CD45 and dim expression of CD3., PMID:40510503
Monoclonal Antibodies Against Myeloid Leukemia Cells: Current Knowledge and Future Directions., PMID:40429716
Nodal Mature Plasmacytoid Dendritic Cell Proliferation in a Patient With Chronic Myelomonocytic Leukemia: A Diagnostic Mimic of Blastic Plasmacytoid Dendritic Cell Neoplasm., PMID:40415500
Immunomodulatory effects of detoxification agents on dendritic cell populations in methamphetamine addiction., PMID:40390118
Enhanced electrochemical immunosensor utilizing pATA/AuNPs for sensitive detection of the leukemia-associated biomarker CD123 in bone marrow supernatant., PMID:40368271
Pharmacodynamic effect of mTOR inhibition-based immunosuppressive therapy on dendritic cell and natural killer cell subsets after renal transplantation., PMID:40289708
Ru(II)-thymine complex suppresses acute myeloid leukemia stem cells by inhibiting NF-κB signaling., PMID:40288174
Hyper-reactivity of CD8+ T cells and high expression of IL-3 correlates with occurrence and severity of Long-COVID., PMID:40287027
Immunohistochemical analysis reveals higher Myxovirus resistance protein 1 expression and increased macrophage count in placentas from patients with systemic rheumatic diseases., PMID:40183958
Combining CD64 and CD123 Biomarkers for Sepsis Early Diagnosis and Severity Assessment via PD-L1 Antibody Affinity Microfluidic (PAAM) Chip in Trace Clinical Samples., PMID:40177943
Immunotherapies Targeting CD123 and CD303: A New Frontier in Treating Blastic Plasmacytoid Dendritic Cell Neoplasm., PMID:40141368
A review of antibody-based immunotherapy clinical trials for adult acute myeloid leukemia (AML): monoclonal antibodies (mAbs) and beyond., PMID:40069930
Immune dysregulation in glycogen storage disease 1b extends beyond neutropenia., PMID:40037121
Venetoclax and hypomethylating agents versus tagraxofusp in older patients with blastic plasmacytoid dendritic cell neoplasm., PMID:39971776
Rapid and Differential Diagnosis of Sepsis Stages Using an Advanced 3D Plasmonic Bimetallic Alloy Nanoarchitecture-Based SERS Biosensor Combined with Machine Learning for Multiple Analyte Identification., PMID:39960361
Clinical, Histopathological, and Therapeutic Features in Lupus Erythematosus Tumidus: A Retrospective Study., PMID:39947587
Single-chain variable fragment affinity tuning can optimize anti-AML CAR-NK cell functionality., PMID:39915004
Blastic plasmacytoid dendritic cell neoplasm: a Swiss case series of a very rare disease and a structured review of the literature., PMID:39877935
A novel label-free method to determine equilibrium dissociation constants of antibodies binding to cell surface proteins., PMID:39870691
The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia., PMID:39830370
ONC213: a novel strategy to resensitize resistant AML cells to venetoclax through induction of mitochondrial stress., PMID:39780285
Clozapine Induces Agranulocytosis via Inflammatory and Hematopoietic Cytokine Induction of the JAK-STAT Signaling Pathway: Evidence From Network Pharmacology and Molecular Docking., PMID:39776289
[Clinical and Pathological Features of Blastic Plasmacytoid Dendritic Cell Neoplasm]., PMID:39743245
Honing CAR T cells to tackle acute myeloid leukemia., PMID:39630061
CD33-CD123 IF-THEN Gating Reduces Toxicity while Enhancing the Specificity and Memory Phenotype of AML-Targeting CAR-T Cells., PMID:39624992
Participation of Semaphorin Family and Plexins in the Clinical Course of Patients with Inflammatory Bowel Disease., PMID:39596507
Loop33 × 123 CAR-T targeting CD33 and CD123 against immune escape in acute myeloid leukemia., PMID:39535595
Hairy cell leukemia (HCL) and HCL-like disorders: present, emergent treatment options and future directions., PMID:39535173
FLAER Revealed Normally Expected Non-PNH FLAER-Dim Immature Myeloid Cells (CD117+/CD34-) In Bone Marrow Aspirates and Could Be Utilized as a Marker of Hierarchical Hematopoiesis., PMID:39478200
Role of IL3RA in a Family with Lumbar Spinal Stenosis., PMID:39456698
BRD4 inhibitor reduces exhaustion and blocks terminal differentiation in CAR-T cells by modulating BATF and EGR1., PMID:39407311
CAR T-cell therapy in acute myeloid leukemia., PMID:39379118
Advancements in leukemia management: Bridging diagnosis, prognosis and nanotechnology (Review)., PMID:39364739
Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia., PMID:39353428
Cytokine-mediated CAR T therapy resistance in AML., PMID:39333315
UDP-glucose ceramide glucosyltransferase specifically upregulated in plasmacytoid dendritic cells regulates type I interferon production upon CpG stimulation., PMID:39307111
4-Methylthiazole triggers apoptosis and mitochondrial disruption in HL-60 cells., PMID:39297923
Looking ahead to targeting macrophages by CAR T- or NK-cells in blood cancers., PMID:39235181
A γδ T cell-IL-3 axis controls allergic responses through sensory neurons., PMID:39232162
Good manufacturing practice-grade generation of CD19 and CD123-specific CAR-T cells using piggyBac transposon and allogeneic feeder cells in patients diagnosed with B-cell non-Hodgkin lymphoma and acute myeloid leukemia., PMID:39192973
[Current state and future prospects of CAR T-cell therapy for myeloid malignancies]., PMID:39098014
Rational combinatorial targeting by adapter CAR-T-cells (AdCAR-T) prevents antigen escape in acute myeloid leukemia., PMID:39095503
Inducible pluripotent stem cells to study human mast cell trajectories., PMID:39038754
Pathogenic role and diagnostic utility of interferon-α in histiocytic necrotizing lymphadenitis., PMID:39032847
Olverembatinib combined with inotuzumab ozogamicin in relapsed refractory Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report., PMID:39029009
[Clinical characteristics and prognosis of childhood acute lymphoblastic leukemia with CD123 expression]., PMID:39014947
CAR-T cell therapy in AML: recent progress and future perspectives., PMID:38963636
IL-3: key orchestrator of inflammation., PMID:38938573
Characterising plasmacytoid and myeloid AXL+ SIGLEC-6+ dendritic cell functions and their interactions with HIV., PMID:38924030
Hairy cell leukemia - etiopathogenesis, diagnosis and modern therapeutic approach., PMID:38882583
For research use only. Not for human or drug use.
