Catalog No.
YHN30301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp28-Asp202
Predicted molecular weight
22.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96E17
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-3C, RAB3C
PIEZO1 attenuates Marfan syndrome aneurysm development through TGF-β signaling pathway inhibition via TGFBR2., PMID:39585648
Citrulline facilitates the glycolysis, proliferation, and metastasis of lung cancer cells by regulating RAB3C., PMID:38770826
Important roles of Hif1a in maternal or adult BPA exposure induced pancreatic injuries., PMID:37460698
CircRNA hsa_circ_0070659 predicts poor prognosis and promotes non-small cell lung cancer (NSCLC) progression via microRNA-377 (miR-377) / Ras-Associated Binding Protein 3C (RAB3C) pathway., PMID:36694911
Overexpression of synaptic vesicle protein Rab GTPase 3C promotes vesicular exocytosis and drug resistance in colorectal cancer cells., PMID:36652260
Clinical identification of expressed proteins in adrenal medullary hyperplasia detected with hypertension., PMID:36583008
The complex, dynamic SpliceOme of the small GTPase transcripts altered by technique, sex, genetics, tissue specificity, and RNA base editing., PMID:36467401
Localization Patterns of RAB3C Are Associated with Murine and Human Sperm Formation., PMID:36295569
Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector., PMID:35871249
Rab3 proteins and cancer: Exit strategies., PMID:33982832
Integrative Multi-omics Analysis to Characterize Human Brain Ischemia., PMID:33939164
Specific Antiproliferative Properties of Proteinaceous Toxin Secretions from the Marine Annelid Eulalia sp. onto Ovarian Cancer Cells., PMID:33445445
Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers., PMID:31871774
SNARE Complex-Associated Proteins in the Lateral Amygdala of Macaca mulatta Following Long-Term Ethanol Drinking., PMID:29944190
A proteomic analysis of contextual fear conditioned rats reveals dynamic modifications in neuron and oligodendrocyte protein expression in the dentate gyrus., PMID:28833751
Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis., PMID:28784136
Convergent evolution of adenosine aptamers spanning bacterial, human, and random sequences revealed by structure-based bioinformatics and genomic SELEX., PMID:23102219
Expression profiling of Rab GTPases reveals the involvement of Rab20 and Rab32 in acute brain inflammation in mice., PMID:22960262
Analysis of Synaptotagmin, SV2, and Rab3 Expression in Cortical Glutamatergic and GABAergic Axon Terminals., PMID:22275882
Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis., PMID:20926670
Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells., PMID:20716109
The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells., PMID:19717423
ApRab3, a biosynthetic Rab protein, accumulates on the maturing phagosomes and symbiosomes in the tropical sea anemone, Aiptasia pulchella., PMID:19110066
A unique residue in rab3c determines the interaction with novel binding protein Zwint-1., PMID:18625232
Interaction of Rab3B with microtubule-binding protein Gas8 in NIH 3T3 cells., PMID:18396146
Rab3A deletion selectively reduces spontaneous neurotransmitter release at the mouse neuromuscular synapse., PMID:16631140
Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity., PMID:16436611
Molecular profiling reveals synaptic release machinery in Merkel cells., PMID:15448211
A complete genetic analysis of neuronal Rab3 function., PMID:15269275
Cloning, mapping, and characterization of the human Rab3C gene., PMID:12296628
Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion., PMID:12167638
Molecular cloning of the mouse homologue of Rab3c., PMID:11573517
Subcellular distribution and function of Rab3A-D in pancreatic acinar AR42J cells., PMID:11563859
Rab3a controls exocytosis in cholecystokinin-secreting cells., PMID:11513847
Carboxyl-methylation of Rab3D in the rat pancreatic acinar tumor cell line AR42J., PMID:11453651
Differential expression of Rab3 isoforms in high- and low-secreting mast cell lines., PMID:11370744
Establishment of variant PC12 subclones deficient in stimulation-secretion coupling., PMID:11341965
Regulation of subcellular distribution of GLUT4 in cardiomyocytes: Rab4A reduces basal glucose transport and augments insulin responsiveness., PMID:10768829
Expression and regulation of RAB3 proteins in osteoclasts and their precursors., PMID:10571685
Molecular analysis of neurotransmitter release., PMID:10488439
Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release., PMID:10407024
Comparison of the effects on secretion in chromaffin and PC12 cells of Rab3 family members and mutants. Evidence that inhibitory effects are independent of direct interaction with Rabphilin3., PMID:10364266
Cloning and localization of Rab3 isoforms in bovine, rat, and human parathyroid glands., PMID:10049764
Subcellular distribution and function of Rab3A, B, C, and D isoforms in insulin-secreting cells., PMID:9973251
Expression of Rab3A in the cortical region in mouse metaphase II eggs., PMID:9437855
Differential expression of Rab3 isoforms during differentiation of pancreatic acinar cell line AR42J., PMID:9245721
Characterization of Rab3A, Rab3B and Rab3C: different biochemical properties and intracellular localization in bovine chromaffin cells., PMID:9164844
Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G proteins., PMID:9020086
Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells., PMID:8886977
Differential expression of rab3 isoforms in oligodendrocytes and astrocytes., PMID:8841986