Catalog No.
PHH31001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CALCRL (Glu23-Glu133).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CGRP type 1 receptor,CGRPR,Calcitonin receptor-like receptor,CALCRL,Calcitonin gene-related peptide type 1 receptor
Purification
Purified by antigen affinity column.
Accession
Q16602
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Quantitative proteomics reveals CLR interactome in primary human cells., PMID:38777147
Expression of the Calcitonin Receptor-like Receptor (CALCRL) in Normal and Neoplastic Tissues., PMID:36835377
Response to erenumab assessed by Headache Impact Test-6 is modulated by genetic factors and arterial hypertension: An explorative cohort study., PMID:36627267
Role of CGRP pathway polymorphisms in migraine: a systematic review and impact on CGRP mAbs migraine therapy., PMID:34330208
Distribution of CGRP and its receptor components CLR and RAMP1 in the rat retina., PMID:28603014
Functional Analysis of the Adrenomedullin Pathway in Malignant Pleural Mesothelioma., PMID:26762744
Adrenomedullin blockade suppresses growth of human hormone-independent prostate tumor xenograft in mice., PMID:24100627
Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo., PMID:23634287
Localization of calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1) in human gastrointestinal tract., PMID:22484227
Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries., PMID:20855369
Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion., PMID:20472035
Expression of adrenomedullin 2/intermedin, a possible reno-protective peptide, is decreased in the kidneys of rats with hypertension or renal failure., PMID:20462970
Effects of adrenomedullin on the glomerular adrenomedullin system in a rat model of anti-thy1 glomerulonephritis., PMID:20431304
Lipopolysaccharide induces calcitonin gene-related peptide in the RAW264.7 macrophage cell line., PMID:20141542
Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic alpha2C receptors., PMID:17614212
Post-endocytic sorting of calcitonin receptor-like receptor and receptor activity-modifying protein 1., PMID:17310067
Expression of calcitonin receptor-like receptor in human vascular tumours., PMID:17021138
Adrenomedullin increases the expression of calcitonin-like receptor and receptor activity modifying protein 2 mRNA in human microvascular endothelial cells., PMID:16899583
Two novel cell specific receptor proteins, CRLR and CD 117 in human glial tumors., PMID:16719406
Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothelial cells and induce its desensitisation by different mechanisms., PMID:16495482
Calcitonin stimulates multiple stages of angiogenesis by directly acting on endothelial cells., PMID:16166333
Adrenomedullin enhances invasion by trophoblast cell lines., PMID:15917349
Evidence for decreased calcitonin gene-related peptide (CGRP) receptors and compromised responsiveness to CGRP of fetoplacental vessels in preeclamptic pregnancies., PMID:15623815
Studies on the effects of the N-terminal domain antibodies of calcitonin receptor-like receptor and receptor activity-modifying protein 1 on calcitonin gene-related peptide-induced vasorelaxation in rat uterine artery., PMID:14960487
The immunohistochemical expression of calcitonin receptor-like receptor (CRLR) in human gliomas., PMID:14747444
Involvement of calcitonin gene-related peptide in control of human fetoplacental vascular tone., PMID:14684361
The function of conserved cysteine residues in the extracellular domain of human receptor-activity-modifying protein., PMID:14644429
Immunohistochemical detection of the calcitonin receptor-like receptor protein in the microvasculature of rat endothelium., PMID:14642779
Expression and distribution of the calcitonin receptor-like receptor in the developing rat heart., PMID:12937976
The localization of adrenomedullin in rat kidney tissue and its inhibitory effect on the growth of cultured rat mesangial cells., PMID:12901533
Expression of calcitonin gene-related peptide receptor components, calcitonin receptor-like receptor and receptor activity modifying protein 1, in the rat placenta during pregnancy and their cellular localization., PMID:12837925
Adrenomedullin is an autocrine/paracrine growth factor for rat vascular smooth muscle cells., PMID:12667639
Calcitonin receptor-like receptor: identification and distribution in human peripheral tissues., PMID:12242482
Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines., PMID:12086988
Expression and distribution of calcitonin receptor-like receptor in human hairy skin., PMID:11814625
Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling., PMID:10882736
For research use only. Not for human or drug use.
