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Anti-HSPB2 Polyclonal Antibody

Catalog #:   PHH24101 Specific References (16) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q16082
Overview

Catalog No.

PHH24101

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HSPB2 (Ala12-Pro182).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

DMPK-binding protein,HSPB2,HspB2,MKBP,Heat shock protein beta-2

Purification

Purified by antigen affinity column.

Accession

Q16082

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with HSPB2 antibody (PHH24101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 21 kDa
    Observed MW: 21 kDa
References

HSP27 induced glaucomatous damage in mice of young and advanced age., PMID:37744880

Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein., PMID:34046506

Unlike estrogens that increase PCSK9 levels post-menopause HSP27 vaccination lowers cholesterol levels and atherogenesis due to divergent effects on PCSK9 and LDLR., PMID:33022407

Simultaneous use of natural adjuvants and cell penetrating peptides improves HCV NS3 antigen-specific immune responses., PMID:31254535

Binge ethanol and MDMA combination exacerbates HSP27 and Trx-1 (biomarkers of toxic cardiac effects) expression in right ventricle., PMID:30708098

HSP27 protects the blood-brain barrier against ischemia-induced loss of integrity., PMID:23469858

Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB., PMID:22023707

Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro., PMID:20465849

Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity., PMID:19109201

Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex., PMID:17510053

p38MAPK inhibition prevents disease in pemphigus vulgaris mice., PMID:16908851

Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains., PMID:16599941

Inactivation of the Akt survival pathway during photoreceptor apoptosis in the retinal degeneration mouse., PMID:16565401

Role of the small heat shock proteins in regulating vascular smooth muscle tone., PMID:15978441

Association of HSPB2, a member of the small heat shock protein family, with mitochondria., PMID:11697892

Transient up-regulation of myotonic dystrophy protein kinase-binding protein, MKBP, and HSP27 in the neonatal myocardium., PMID:10355872

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-HSPB2 Polyclonal Antibody [PHH24101]
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