Catalog No.
PHH24101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HSPB2 (Ala12-Pro182).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DMPK-binding protein,HSPB2,HspB2,MKBP,Heat shock protein beta-2
Purification
Purified by antigen affinity column.
Accession
Q16082
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
HSP27 induced glaucomatous damage in mice of young and advanced age., PMID:37744880
Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein., PMID:34046506
Unlike estrogens that increase PCSK9 levels post-menopause HSP27 vaccination lowers cholesterol levels and atherogenesis due to divergent effects on PCSK9 and LDLR., PMID:33022407
Simultaneous use of natural adjuvants and cell penetrating peptides improves HCV NS3 antigen-specific immune responses., PMID:31254535
Binge ethanol and MDMA combination exacerbates HSP27 and Trx-1 (biomarkers of toxic cardiac effects) expression in right ventricle., PMID:30708098
HSP27 protects the blood-brain barrier against ischemia-induced loss of integrity., PMID:23469858
Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB., PMID:22023707
Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro., PMID:20465849
Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity., PMID:19109201
Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex., PMID:17510053
p38MAPK inhibition prevents disease in pemphigus vulgaris mice., PMID:16908851
Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains., PMID:16599941
Inactivation of the Akt survival pathway during photoreceptor apoptosis in the retinal degeneration mouse., PMID:16565401
Role of the small heat shock proteins in regulating vascular smooth muscle tone., PMID:15978441
Association of HSPB2, a member of the small heat shock protein family, with mitochondria., PMID:11697892
Transient up-regulation of myotonic dystrophy protein kinase-binding protein, MKBP, and HSP27 in the neonatal myocardium., PMID:10355872
For research use only. Not for human or drug use.
