Catalog No.
PHH18301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TAB1 (Leu189-Pro439).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
MAP3K7IP1,TGF-beta-activated kinase 1-binding protein 1,TAK1-binding protein 1,TGF-beta-activated kinase 1 and MAP3K7-binding protein 1,Mitogen-activated protein kinase kinase kinase 7-interacting protein 1,TAB1
Purification
Purified by antigen affinity column.
Accession
Q15750
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Aberrant B-Cell Activation in Systemic Lupus Erythematosus., PMID:36590680
Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons., PMID:24674717
O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release., PMID:22307082
Toll-like receptor 2 monoclonal antibody or/and Toll-like receptor 4 monoclonal antibody increase counts of Lactobacilli and Bifidobacteria in dextran sulfate sodium-induced colitis in mice., PMID:21722182
Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex., PMID:18021073
Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling., PMID:15743758
Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2., PMID:15590691
Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells., PMID:15218018
Requirement of soluble factors produced by bone marrow stromal cells on the growth of novel established human myeloma cell line., PMID:12579318
Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load., PMID:11884412
Influence of various combinations of specific antibody dose and affinity on tissue imipramine redistribution., PMID:9776341
Redistribution of imipramine from regions of the brain under the influence of circulating specific antibodies., PMID:9572296
Multiepitope polypeptide of the HIV-1 envelope induces neutralizing monoclonal antibodies against V3 loop., PMID:7517147
Localization of transforming growth factor alpha in the human placenta and decidua: role in trophoblast growth., PMID:8286584