Catalog No.
PHH18201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MYLK (Thr1748-Glu1914).
Tested applications
ELISA: 1:2000-1:8000, IHC: 1:50-1:100, WB: 1:500-1:4000
Target
MLCK1,smMLCK,MYLK1,KRP,Kinase-related protein,MLCK,MYLK,Myosin light chain kinase,smooth muscle,Telokin
Concentration
1.1 mg/ml
Purification
Purified by antigen affinity column.
Accession
Q15746
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
CT45A1-mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell-in-cell structure, potentiating the progression of microsatellite instability-high colorectal cancer., PMID:39322998
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential., PMID:34548480
Distinct molecular subtypes of uterine leiomyosarcoma respond differently to chemotherapy treatment., PMID:28893210
Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles., PMID:25637593
MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells., PMID:24486510
Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury., PMID:20139351