Catalog No.
YVV08602
Expression system
E. coli
Species
Hepatitis C virus genotype 1a (isolate H77) (HCV)
Protein length
Glu384-Glu661
Predicted molecular weight
33.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P27958
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Genome polyprotein, Core protein precursor, Envelope glycoprotein E2, NS1, gp68, gp70
HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development., PMID:34069740
Mutations in different regions of the genome of hepatitis C virus genotype 1b and association with response to interferon therapy., PMID:23064792
[Cloning and sequencing of cDNA of E2/NS1 gene of hepatitis C virus]., PMID:15617335
[Expression of hepatitis C viral structure protein by recombinant vaccinia virus]., PMID:15617243
Sequential changes of hepatitis C virus antibody profiles during treatment of chronic hepatitis C of genotype 1b: pretreatment antibody response to E2/NS1 correlated sustained response., PMID:15188075
[Cloning and sequence analysis of E1, E2/NS1 region of genotype 2a hepatitis C virus genome]., PMID:12870013
[Significance of polypeptide antigen of HCVE2/NS1 relative conservation region in detection of anti-HCV]., PMID:12759957
Expression and purification of E2/NS1 protein of hepatitis C virus and detection of anti-E2/NS1 antibodies in chronic liver disease patients., PMID:12595764
Identification of human hepatocyte protein(s), which binds specifically to the recombinant envelope-2/non-structural-1 protein of hepatitis C virus., PMID:12191777
Antibody response to E2 glycoprotein induced in mice by immunization with plasmid DNA containing sequence derived from a Chinese genotype III/2a isolate of hepatitis C virus., PMID:11593587
Molecular design and immunogenicity studies of multiple antigenic peptide corresponding to envelope glycoprotein hypervariable region 1 of hepatitis C virus., PMID:11503045
Predominance of antibodies to hepatitis C virus envelope proteins in various disease statuses of hepatitis C., PMID:11394572
[Expression of glycoprotein hepatitis C virus in mammalian cell and application of purified protein for detection of antibody against E2 in hepatitis C patients]., PMID:10715790
[Sequence diversity of genotype II/1b hepatitis C virus (HCV) HVR1 of 46 patients in Beijing areas]., PMID:10488415
Degree and distribution of variability in the 5' untranslated, E1, E2/NS1 and NS5 regions of the hepatitis C virus (HCV)., PMID:9751009
Differences in hepatitis C virus quasispecies composition between liver, peripheral blood mononuclear cells and plasma., PMID:9225024
Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver., PMID:9159034
Antibody response to E2/NS1 hepatitis C virus protein in patients with acute hepatitis C., PMID:9076628
Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients., PMID:8959633
Comparison of hypervariable regions (HVR1 and HVR2) in positive- and negative-stranded hepatitis C virus RNA in cancerous and non-cancerous liver tissue, peripheral blood mononuclear cells and serum from a patient with hepatocellular carcinoma., PMID:8760588
Discrepancy of hepatitis C virus genotypes as determined by phylogenetic analysis of partial NS5 and core sequences., PMID:8818959
Lack of correlation between different hepatitis C virus screening and confirmatory assays., PMID:8793841
Quantitative analysis of antibody to hepatitis C virus envelope 2 glycoprotein in patients with chronic hepatitis C virus infection., PMID:8621173
Hepatitis C in human immunodeficiency virus-coinfected patients: increased variability in the hypervariable envelope coding domain., PMID:8666318
Sequence variation of the hypervariable region in HCV carriers with normal ALT levels: a comparison with symptomatic carriers., PMID:9013492
Fraction-specific populations of the hypervariable region of the hepatitis C virus in a patient with cryoglobulinemia., PMID:7595420
Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses., PMID:7815542
Prevalence of hepatitis C virus sequence variants in South-East Asia., PMID:7844535
The serology of hepatitis C virus (HCV) infection: antibody crossreaction in the hypervariable region 1., PMID:7503672
Influence of antibodies to the hypervariable region of E2/NS1 glycoprotein on the selective replication of hepatitis C virus in chimpanzees., PMID:7941335
[Evolution of hepatitis C virus (HCV) viremia and adaptation of HCV in persistent infection in patients with acute hepatitis]., PMID:7521430
[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy in relation to clinical course]., PMID:7521410
Adaptation of hepatitis C virus for persistent infection in patients with acute hepatitis., PMID:7545924
Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells., PMID:8212557
Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants., PMID:7689636
Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection., PMID:8382721
Antigenic regions within the hepatitis C virus envelope 1 and non-structural proteins: identification of an IgG3-restricted recognition site with the envelope 1 protein., PMID:7680297
[Expression of hepatitis C virus genome]., PMID:7681882
Persistence of hepatitis B and hepatitis C viral genomes in primary liver cancers from HBsAg-negative patients: a study of a low-endemic area., PMID:8380790
Expression of HCV E2/NS1 protein as a fusion protein with maltose binding protein: detection of anti-E2/NS1 antibody in chronic liver disease., PMID:7686121
Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease., PMID:1314578
Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein., PMID:1655961
Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins., PMID:1846505
Hepatitis C virus (HCV)-RNA in non-A, non-B chronic hepatitis in France. Nucleotide sequence of a French HCV isolate., PMID:1668329
For research use only. Not for human or drug use.
