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Research Grade Efercoleukin Alfa

Catalog #:   DHF36805 Specific References (50) DATASHEET
Isotype: Human IgG1 Fc fragment fused to IL2RB disulfide bridged to human IgG1 Fc fragment fused to human IL2
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Accession: P60568 & P14784
Overview

Catalog No.

DHF36805

Expression system

Mammalian Cells

Species reactivity

Human

Isotype

Human IgG1 Fc fragment fused to IL2RB disulfide bridged to human IgG1 Fc fragment fused to human IL2

Target

IL2, IL-2, Aldesleukin, Interleukin-2, TCGF, T-cell growth factor, IL-2R subunit beta, Interleukin-15 receptor subunit beta, IL2RB, IL-2 receptor subunit beta, CD122, High affinity IL-2 receptor subunit beta, p75, Interleukin-2 receptor subunit beta, IL-2RB, p70-75, IL15RB

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P60568 & P14784

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CAS: 2760549-52-6

Clone ID

Efercoleukin Alfa

Data Image
References

Rash associated with antibiotic administration in patients with infectious mononucleosis: a systematic review and meta-analysis., PMID:40512251

Integrative Analysis of Drug Co-Prescriptions in Peritoneal Dialysis Reveals Molecular Targets and Novel Strategies for Intervention., PMID:40507495

International Fibrolamellar Cancer Registry: Opportunities and Challenges., PMID:40499052

Rare types of alpha-1-antitrypsin deficency in the same family: Pi*Mmalton and Pi*Plowell., PMID:40497812

Persistent Atelectasis Prevalence and Incidence in Pediatric Critical Care., PMID:40497177

Validation of a handheld electrocardiogram 6 lead recorder to obtain chest lead equivalents: An Africa Heart Rhythm Association study., PMID:40496591

GX-I7, a long-acting IL-7, safely and effectively increased peripheral CD8+/CD4+ T cells and TILs in patients with locally advanced or metastatic solid tumours., PMID:40490502

Exploring Antimalarial Activity of Drugs using Weighted Atomic Vectors and Artificial Intelligence., PMID:40485561

Efimosfermin alfa (BOS-580), a long-acting FGF21 analogue, in participants with phenotypic metabolic dysfunction-associated steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2a trial., PMID:40484014

Enzyme replacement therapies in adults with Pompe disease: from trials to real-world data., PMID:40471681

Safety, pharmacokinetics and pharmacodynamics of Efsubaglutide Alfa in healthy participants: A randomised, dose-escalation phase 1 study., PMID:40470753

Successful treatment of hairy cell leukaemia with pegylated interferon-alpha-2A., PMID:40469412

Therapeutic efficacy of budesonide suspension combined with poractant alfa injection for neonatal respiratory distress syndrome and its effect on serum ferritin and PAI-1 expressions., PMID:40469168

Italian guidelines for the diagnosis and management of gastro-esophageal reflux disease: Joint consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), and General Medicine (SIMG)., PMID:40450492

The Mini-COMET Clinical Trial: Safety and Efficacy of Avalglucosidase Alfa after 97 Weeks of Treatment in Children with Infantile-Onset Pompe Disease Previously Treated with Alglucosidase Alfa., PMID:40449831

Preclinical Safety., PMID:40445826

Mean Corpuscular Volume Is Not a Reliable Predictor of Iron Deficiency in Patients With Chronic Kidney Disease: A Post-Hoc Analysis of the BRIGHTEN Trial., PMID:40443639

Mobility and Quality of Life in Children with Paediatric-Onset Hypophosphatasia Treated with Asfotase Alfa: Results from UK Managed Access Agreement., PMID:40439960

Less Invasive Surfactant Administration (LISA) versus Intubation Surfactant Extubation (InSurE) technique using higher volume surfactant in management of neonates with respiratory distress syndrome: an open-label randomized controlled trial., PMID:40439732

Life-Threatening Pharyngolaryngeal Hematoma in a Patient With Hemophilia A., PMID:40438813

Global Variation in Lipoprotein(a) Levels Among Patients With Coronary Heart Disease: Insights From the INTERASPIRE Study and Implications for Emerging Lp(a)-Lowering Therapies., PMID:40436467

Multistrain Probiotics Plus Vitamin D Improve Gut Barrier Function and Gut Microbiota Composition in Irritable Bowel Syndrome Without Constipation: Results from a Double-Blind, Randomized, Placebo-Controlled Trial., PMID:40431448

Exploring Multivalent Architectures for Binding and Stabilization of N-Acetylgalactosamine 6-Sulfatase., PMID:40430394

Current status of the immunogenicity of enzyme replacement therapy in fabry disease., PMID:40420145

Phenotypic and Genotypic Spectrum of Indian Patients with Hypophosphatasia., PMID:40416455

Therapeutic adherence in inflammatory bowel disease: User guide from a multidisciplinary modified Delphi consensus., PMID:40414777

[Acid sphingomyelinase deficiency: A review]., PMID:40414757

A global comparison of hepatitis B & C drug pricing., PMID:40414600

Fosfomycin for the treatment of patients with bacterial prostatitis: a systematic review., PMID:40410452

Markedly discordant hypophosphatasia in a young girl., PMID:40409424

A Theoretical and Experimental Study of Carbonized Lignin from Alfa Fibers as a Clay-Based Adsorbent., PMID:40402651

Robust longitudinal neuropsychological norms in Spanish individuals with nonpathological Alzheimer's disease biomarkers., PMID:40402619

Development and description of a porcine model of combat casualty care for traumatic-hemorrhagic shock research and medical training., PMID:40402209

Reversal of anticoagulation in patients with intracerebral haemorrhage related to oral anticoagulants: State of the evidence., PMID:40401655

Effects of erythropoietin on cardiac morphometry in exercised male and female adolescent rats., PMID:40400735

Good clinical practice recommendations for the diagnosis and treatment of functional dyspepsia: An expert review from the Asociación Mexicana de Gastroenterología., PMID:40399175

Defining clinically meaningful thresholds for forced vital capacity in patients with neuromuscular disorders: Lessons learned from the COMET study in Pompe disease., PMID:40397025

Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer, a study with 5-year follow-up: a plain language summary., PMID:40396643

Case of Gynandroblastoma of the Ovary with Raised AFP and Associated DICER 1 Mutation., PMID:40390890

Recurrence risk factors for chronic hepatitis B virus-infected patients who achieve functional cure with pegylated interferon-α-2b-based therapy: a multicenter pilot study., PMID:40390028

SGLT2 inhibitor with and without ALDosterone AntagonIst for heart failure with preserved ejection fraction: Design paper., PMID:40388563

Assisting the Diagnosis of Cirrhosis in Chronic Hepatitis C Patients Based on Machine Learning Algorithms: A Novel Non-Invasive Approach., PMID:40384539

Immune-mediated adverse events and overall survival with tremelimumab plus durvalumab and durvalumab monotherapy in unresectable hepatocellular carcinoma: HIMALAYA phase 3 randomized clinical trial., PMID:40384092

Real-world experience with the diagnosis of bile acid malabsorption (BAM) using serum 7-alpha-C4 and 48-hour stool bile acids., PMID:40383704

Venous thromboembolism in professional drivers of automatic transmission vehicles: an underestimated occupational risk?, PMID:40382788

Author's reply: "Comment on "Italian validation of the IBD-disk tool for the assessment of disability in inflammatory bowel diseases""., PMID:40379540

Long-Term Transfusion Independence with Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent-Naive, Lower-Risk Myelodysplastic Syndromes in the COMMANDS Trial., PMID:40377899

Correction: Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera., PMID:40377864

HBV-specific T-cell function is nonenhanced by tenofovir-induced decline in HBV viremia or HBsAg titer in chronic hepatitis B., PMID:40377525

Immune-Related Adverse Events Are Associated With Improved Outcomes After Immune Checkpoint Inhibitor Treatment in Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis., PMID:40377239

Datasheet
$ 426
Product specifications
100 μg 426 1 mg 1704

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For research use only. Not for human or drug use.

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Research Grade Efercoleukin Alfa [DHF36805]
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