Catalog No.
DHC04206
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Chimeric
Isotype
IgG4-kappa
Clonality
Monoclonal
Target
Plasma thromboplastin antecedent, PTA, Coagulation factor XI, F11, FXI
Concentration
4.38 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03951
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
CAS: 2704554-77-6
Clone ID
Gruticibart
Genomic insights of the co-existence of blaOXA-23, blaOXA-91, blaNDM-1 harboring carbapenem-resistant Acinetobacter baumannii isolates from the intensive care units environment in Shanghai., PMID:40505723
Anticoagulation in Atrial Fibrillation: Is a Paradigm Shift From Xa to XIa Inhibitors on the Horizon?, PMID:40439401
A Systematic Review of Safety and Efficacy of Factor XI/XIa Inhibitors in Patients With ESKD on Hemodialysis., PMID:39810768
Preventing Coagulation of Extracorporeal System During Hemodialysis., PMID:39503455
Metformin use is associated with lower risks of dementia, anxiety and depression: The Hong Kong diabetes study., PMID:38796398
Factor XI Inhibition for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Undergoing Central Line Placement: A Phase 2 Clinical Trial., PMID:37970718
Factor XI Inhibition With Heparin Reduces Clot Formation in Simulated Pediatric Extracorporeal Membrane Oxygenation., PMID:37801726
Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis., PMID:35638310
The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial., PMID:34086880
The Safety and Efficacy of Novel Agents Targeting Factors XI and XII in Early Phase Human Trials., PMID:31216587
AB023, A Novel Antibody That Binds Factor XI and Blocks Its Activation by Factor XIIa., PMID:30917049
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial., PMID:30700130
AB023, novel polyene antibiotics. II. Isolation and structure determination., PMID:8468240
AB023, novel polyene antibiotics. I. Taxonomy of the producing organism, fermentation and antifungal activity., PMID:8468239
For research use only. Not for human or drug use.
