Catalog No.
DHE63502
Expression system
Mammalian Cells
Species reactivity
Human
Isotype
VHH-hFc
Clonality
Monoclonal
Target
CX3CR1, Beta chemokine receptor-like 1, Fractalkine receptor, CMK-BRL1, GPR13, CMKBRL1, CX3C chemokine receptor 1, V28, G-protein coupled receptor 13, C-X3-C CKR-1, CMK-BRL-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P49238
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
BI 655089,BI655089,BI-655089
Clone ID
BI 655089
A single dose of a CD137 antibody-drug conjugate protects nonhuman primate allogeneic HCT recipients against acute GVHD., PMID:40504994
CX3CR1+ Monocytes/Macrophages Promote Regional Immune Injury in Mesangial Proliferative Glomerulonephritis through Crosstalk with Activated Mesangial Cells., PMID:40458609
Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis., PMID:40455292
Glucocorticoid boluses followed by tocilizumab in giant cell arteritis patients: effects on peripheral blood monocytes and lymphocytes., PMID:40213553
Single-cell immune profiling of third trimester pregnancies defines importance of chemokine receptors and prevalence of CMV-induced NK cells in the periphery and decidua., PMID:40196247
Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration., PMID:40111356
Structures of respiratory syncytial virus G bound to broadly reactive antibodies provide insights into vaccine design., PMID:40082629
Activation of proresolving macrophages in dorsal root ganglia attenuates persistent arthritis pain., PMID:40063821
Inhibition of aortic CX3CR1+ macrophages mitigates thoracic aortic aneurysm progression in Marfan syndrome in mice., PMID:39817456
Metabolic-Immune Suppression Mediated by the SIRT1-CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma., PMID:39783838
TNF-α Suppression Attenuates Limbal Stem Cell Damage in Ocular Injury., PMID:39626088
Dorsal root ganglia CSF1+ neuronal subtypes have different impact on macrophages and microglia after spared nerve injury., PMID:39581686
Expression of IL-7RαlowCX3CR1+ CD8+ T Cells and α4β7 Integrin Tagged T Cells Related to Mucosal Immunity in Children with Inflammatory Bowel Disease., PMID:39563840
Chromatin remodelling drives immune cell-fibroblast communication in heart failure., PMID:39443808
Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?, PMID:39427326
The immunological pathogenesis of IgG4-related disease categorized by clinical characteristics., PMID:39306708
Chemokine receptors in COVID-19 infection., PMID:39260938
Macrophage-Expressed Coagulation Factor VII Promotes Adverse Cardiac Remodeling., PMID:39234697
The role of respiratory syncytial virus G protein in immune cell infection and pathogenesis., PMID:39217853
ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltration., PMID:39152118
The Central Conserved Peptides of Respiratory Syncytial Virus G Protein Enhance the Immune Response to the RSV F Protein in an Adenovirus Vector Vaccine Candidate., PMID:39066445
Phenotypic characterisation of bovine alveolar macrophages reveals two major subsets with differential expression of CD163., PMID:38951667
VNN2-expressing circulating monocytes exhibit unique functional characteristics and are decreased in patients with primary Sjögren's syndrome., PMID:38936146
Identification of different functions of CD8+ T cell subpopulations by a novel monoclonal antibody., PMID:38922845
Alirocumab boosts antioxidant status and halts inflammation in rat model of sepsis-induced nephrotoxicity via modulation of Nrf2/HO-1, PCSK9/HMGB1/NF-ᴋB/NLRP3 and Fractalkine/CX3CR1 hubs., PMID:38889644
Virus neutralization assays for human respiratory syncytial virus using airway organoids., PMID:38884678
Peripheral CX3CR1+ T cells combined with PD-1 blockade therapy potentiates the anti-tumor efficacy for lung cancer., PMID:38798746
Discrepant Phenotyping of Monocytes Based on CX3CR1 and CCR2 Using Fluorescent Reporters and Antibodies., PMID:38786041
Chemokines and lymphocyte homing in Sjögren's syndrome., PMID:38736890
Anti-CX3CL1 (fractalkine) monoclonal antibody attenuates lung and skin fibrosis in sclerodermatous graft-versus-host disease mouse model., PMID:38702742
Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling., PMID:38660801
Mucosal Immunity Related to CD8+ T Lymphocytes in Children with Helicobacter pylori Gastritis., PMID:38249639
ProBDNF contributed to patrolling monocyte infiltration and renal damage in systemic lupus erythematosus., PMID:38142902
Monocyte populations are involved in the pathogenesis of experimental epidermolysis bullosa acquisita., PMID:38116004
Identification of dendritic cell precursor from the CD11c+ cells expressing high levels of MHC class II molecules in the culture of bone marrow with FLT3 ligand., PMID:38094300
CSF1R inhibition promotes neuroinflammation and behavioral deficits during graft-versus-host disease in mice., PMID:38048572
Contribution of macrophages to neural survival and intracochlear tissue remodeling responses following cochlear implantation., PMID:37974203
CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury., PMID:37922341
Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling., PMID:37824022
The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy., PMID:37771579
Prolonged cytopenia following CD19 CAR T cell therapy is linked with bone marrow infiltration of clonally expanded IFNγ-expressing CD8 T cells., PMID:37586321
Contribution of macrophages to intracochlear tissue remodeling responses following cochlear implantation and neural survival., PMID:37461619
Immunogenicity and protective efficacy of an RSV G S177Q central conserved domain nanoparticle vaccine., PMID:37457705
Spinal Cathepsin S promotes visceral hypersensitivity via FKN/CX3CR1/p38 MAPK signaling pathways., PMID:37347150
Differential Effects of Anti-PD-1/PD-L1 Checkpoint Inhibitors on Adhesion Molecules and Cytokine Secretion by THP-1 Monocytes., PMID:37247886
CX3CL1 induces cell migration and invasion through ICAM-1 expression in oral squamous cell carcinoma cells., PMID:37082943
CX3CR1 modulates SLE-associated glomerulonephritis and cardiovascular disease in MRL/lpr mice., PMID:37060359
Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584., PMID:36993977
Anti-G protein antibodies targeting the RSV G protein CX3C chemokine region improve the interferon response., PMID:36938145
Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study., PMID:36917594
For research use only. Not for human or drug use.
