Catalog No.
PHG70501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NID2 (Gly1107-Gly1373).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Osteonidogen,NID-2,Nidogen-2,NID2
Purification
Purified by antigen affinity column.
Accession
Q14112
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Subcutaneous Adipose Tissue-Secreted Proteins as Endocrine Regulators of Physical and Cognitive Function in Older Adults., PMID:40502786
Matrix mineralization controls gene expression in osteoblastic cells., PMID:30193837
Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts., PMID:29760157
Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors., PMID:25807551
Epithelial basement membrane proteins perlecan and nidogen-2 are up-regulated in stromal cells after epithelial injury in human corneas., PMID:25797478
Alterations in basement membrane immunoreactivity of the diabetic retina in three diabetic mouse models., PMID:23263623
Different domains in nidogen-1 and nidogen-2 drive basement membrane formation in skin organotypic cocultures., PMID:22623588
Absence of the basement membrane component nidogen 2, but not of nidogen 1, results in increased lung metastasis in mice., PMID:22260998
Genome-wide identification of possible methylation markers chemosensitive to targeted regimens in colorectal cancers., PMID:21850381
Deposition of nidogens and other basement membrane proteins in the young and aging mouse retina., PMID:19829017
The autoantigen in anti-p200 pemphigoid is synthesized by keratinocytes and fibroblasts and is distinct from nidogen-2., PMID:17637825
Involvement of specific laminins and nidogens in the active remodeling of the basal lamina of labial salivary glands from patients with Sjögren's syndrome., PMID:17075843
Laminin gamma3 chain binds to nidogen and is located in murine basement membranes., PMID:15824114
Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens., PMID:12243745
Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan., PMID:11493006
Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues., PMID:10934193
Ultrastructural colocalization of nidogen-1 and nidogen-2 with laminin-1 in murine kidney basement membranes., PMID:10766264
Nidogen-2: a new basement membrane protein with diverse binding properties., PMID:9733643