Catalog No.
EHB39502
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Arg258
Predicted molecular weight
55.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O76036
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LY94, Natural cytotoxicity triggering receptor 1, Natural killer cell p46-related protein, NK cell-activating receptor, NK-p46, CD335, NKp46, NCR1, hNKp46, Lymphocyte antigen 94 homolog
Effects of Limosilactobacillus fermentum KBL375 on Immune Enhancement and Gut Microbiota Composition in Cyclophosphamide-Induced Immunosuppressed Mice., PMID:39885060
A novel NKp80-based strategy for universal identification of normal, reactive and tumor/clonal natural killer-cells in blood., PMID:39040115
TRAIL-conjugated liposomes that bind natural killer cells to induce colorectal cancer cell apoptosis., PMID:37772330
Response to Bovine Viral Diarrhea Virus in Heifers Vaccinated with a Combination of Multivalent Modified Live and Inactivated Viral Vaccines., PMID:36992412
Evaluation of oxidized beta-carotene on sow and piglet immune systems, sow reproductive performance, and piglet growth., PMID:36857130
A blinded multicenter investigation: Accentuated NK lymphocyte CD335 (NKp46) expression predicts reproductive failures after IVF., PMID:36265608
Characterization of the immune system of Ellegaard Göttingen Minipigs - An important large animal model in experimental medicine., PMID:36203585
CD56bright CD16- natural killer cells as an important regulatory mechanism in chronic graft-versus-host disease., PMID:36200416
Superovulation with gonadotropin-releasing hormone agonist or chorionic gonadotropin for ovulation trigger differentially affects leukocyte populations in the peri-implantation mouse uterus., PMID:35559753
Blockade of inhibitory killer cell immunoglobulin-like receptors and IL-2 triggering reverses the functional hypoactivity of tumor-derived NK-cells in glioblastomas., PMID:35474089
Co-expression of NKp46 with activating or inhibitory receptors on, and cytokine production by, uterine endometrial NK cells in recurrent pregnancy loss., PMID:33930666
Systems Biology behind Immunoprotection of Both Sheep and Goats after Sungri/96 PPRV Vaccination., PMID:33785572
The immune potential of decidua-resident CD16+CD56+ NK cells in human pregnancy., PMID:33583640
A Bovine Enteric Mycobacterium Infection Model to Analyze Parenteral Vaccine-Induced Mucosal Immunity and Accelerate Vaccine Discovery., PMID:33329565
Seasonal heat load is more potent than the degree of body weight loss in dysregulating immune function by reducing white blood cell populations and increasing inflammation in Holstein dairy cows., PMID:32896401
Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases., PMID:32182948
Elimination of erroneous results related to bovine mononuclear cell immunophenotyping by antibodies binding to Fc receptors., PMID:31307671
Symposium review: Immunological detection of the bovine conceptus during early pregnancy., PMID:30712941
A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets., PMID:30288342
A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors., PMID:30080893
Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer., PMID:30037009
Immunological impact of Wharton's Jelly mesenchymal stromal cells and natural killer cell co-culture., PMID:29380244
Parasitological and immunological evaluation of cattle experimentally infected with Trypanosoma vivax., PMID:29309784
CD335 (NKp46)+ T-Cell Recruitment to the Bovine Upper Respiratory Tract during a Primary Bovine Herpesvirus-1 Infection., PMID:29114252
Control of the HIV-1 DNA Reservoir Is Associated In Vivo and In Vitro with NKp46/NKp30 (CD335 CD337) Inducibility and Interferon Gamma Production by Transcriptionally Unique NK Cells., PMID:28956765
Exposure to silver nanoparticles affects viability and function of natural killer cells, mostly via the release of ions., PMID:28721573
Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression., PMID:28396119
The PD-1/B7-H1 pathway modulates the natural killer cells versus mouse glioma stem cells., PMID:26266810
NKp46 regulates the production of serine proteases and IL-22 in human mast cells in urticaria pigmentosa., PMID:25940096
Highly purified mycobacterial phosphatidylinositol mannosides drive cell-mediated responses and activate NKT cells in cattle., PMID:25499010
α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics., PMID:25224412
Expression of the activating receptor, NKp46 (CD335), in human natural killer and T-cell neoplasia., PMID:24225754
Characterization of the Th profile of the bovine endometrium during the oestrous cycle and early pregnancy., PMID:24204576
Identification of immune traits correlated with dairy cow health, reproduction and productivity., PMID:23776543
Innate and adaptive immune responses to the major Parietaria allergen Par j 1 in healthy subjects., PMID:23332216
NKp46 expression discriminates porcine NK cells with different functional properties., PMID:22539298
Neonatal rhinovirus infection induces mucous metaplasia and airways hyperresponsiveness., PMID:22331068
Innate immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1)., PMID:22212381
Mucosal dendritic cell subpopulations in the small intestine of newborn calves., PMID:21527286
Rapid and transient activation of γδ T cells to IFN-γ production, NK cell-like killing, and antigen processing during acute virus infection., PMID:21383249
Bovine natural killer cells., PMID:19339058
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil., PMID:18838519
Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus., PMID:18564343
Bovine NK cells acquire cytotoxic activity and produce IFN-gamma after stimulation by Mycobacterium bovis BCG- or Babesia bovis-exposed splenic dendritic cells., PMID:18514329
Bovine WC1(-) gammadeltaT cells incubated with IL-15 express the natural cytotoxicity receptor CD335 (NKp46) and produce IFN-gamma in response to exogenous IL-12 and IL-18., PMID:18329100
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46., PMID:17360655
The Eighth Human Leucocyte Differentiation Antigen (HLDA8) Workshop: natural killer cell section report., PMID:16157321
For research use only. Not for human or drug use.
