Catalog No.
RHG42205
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Target
Phospho-TDP43 (Ser403, Ser404), pTDP43(403/404), phospho TDP-43 (Ser409/Ser410)
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13148
Applications
ELISA, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2033
Targeted proteomic biomarker profiling using NULISA in a cohort enriched with risk for Alzheimer's disease and related dementias., PMID:40318118
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD., PMID:39363348
Neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases., PMID:39160362
Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain., PMID:37118836
Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions., PMID:36592411
Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP., PMID:33300249
Distinct molecular patterns of TDP-43 pathology in Alzheimer's disease: relationship with clinical phenotypes., PMID:32349792
C-terminal and full length TDP-43 specie differ according to FTLD-TDP lesion type but not genetic mutation., PMID:31266542
Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration., PMID:28877758
Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes., PMID:27338935
Cytoplasmic TDP-43 accumulation in cells of the adrenal medulla in individuals with or without amyotrophic lateral sclerosis., PMID:25039310
Molecular markers for granulovacuolar degeneration are present in rimmed vacuoles., PMID:24312256
Classification of FTLD-TDP cases into pathological subtypes using antibodies against phosphorylated and non-phosphorylated TDP43., PMID:24252630
Accumulation of phosphorylated TDP-43 in the CNS of a patient with Cockayne syndrome., PMID:23581709
Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis., PMID:23320755
Comparison of phosphorylated TDP-43-positive inclusions in oculomotor neurons in patients with non-ALS and ALS disorders., PMID:22257502
Co-occurrence of argyrophilic grain disease in sporadic amyotrophic lateral sclerosis., PMID:21702760
Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43., PMID:21118398
Numerous FUS-positive inclusions in an elderly woman with motor neuron disease., PMID:20667018
Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord., PMID:20379728
For research use only. Not for human or drug use.
