Catalog No.
RHN26901
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
PN3, Voltage-gated sodium channel subunit alpha Nav1.8, Peripheral nerve sodium channel 3, Sodium channel protein type 10 subunit alpha, Sodium channel protein type X subunit alpha, hPN3, SCN10A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N134/12
Nerve growth factor-mediated Na+ channel plasticity of bladder afferent neurons in mice with spinal cord injury., PMID:35367467
Peripheral Voltage-Gated Cation Channels in Neuropathic Pain and Their Potential as Therapeutic Targets., PMID:35295464
New approaches to the design of analgesic medicinal substances., PMID:34425056
Chemogenetic Inhibition of Pain Neurons in a Mouse Model of Osteoarthritis., PMID:28380690
Pathogenesis of abdominal pain in bowel obstruction: role of mechanical stress-induced upregulation of nerve growth factor in gut smooth muscle cells., PMID:28079757
Expression of 5-HT3 receptors and TTX resistant sodium channels (Na(V)1.8) on muscle nerve fibers in pain-free humans and patients with chronic myofascial temporomandibular disorders., PMID:25261281
The voltage-gated sodium channel nav1.8 is expressed in human sperm., PMID:24086692
Localisation of SCN10A gene product Na(v)1.8 and novel pain-related ion channels in human heart., PMID:21646736
Fixative composition alters distributions of immunoreactivity for glutaminase and two markers of nociceptive neurons, Nav1.8 and TRPV1, in the rat dorsal root ganglion., PMID:20026672
Functional tetrodotoxin-resistant Na(+) channels are expressed presynaptically in rat dorsal root ganglia neurons., PMID:19162133
Involvement of voltage-gated sodium channel Na(v)1.8 in the regulation of the release and synthesis of substance P in adult mouse dorsal root ganglion neurons., PMID:18845912
Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat., PMID:18806059
Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain., PMID:17950013
Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor., PMID:16157274
Localization of the Nav1.8 sodium channel isoform at nodes of Ranvier in normal human radicular tooth pulp., PMID:15854746
Upregulation and colocalization of p75 and Nav1.8 in Purkinje neurons in experimental autoimmune encephalomyelitis., PMID:15464262
Ibuprofen blocks changes in Na v 1.7 and 1.8 sodium channels associated with complete Freund's adjuvant-induced inflammation in rat., PMID:15219259
Tetrodotoxin-resistant sodium channels Na(v)1.8/SNS and Na(v)1.9/NaN in afferent neurons innervating urinary bladder in control and spinal cord injured rats., PMID:12560118
Annexin II light chain regulates sensory neuron-specific sodium channel expression., PMID:12050667
Ankyrin G and voltage gated sodium channels colocalize in human neuroma--key proteins of membrane remodeling after axonal injury., PMID:11950515
Distinct potassium channels on pain-sensing neurons., PMID:11698689
Glial cells have heart: rH1 Na+ channel mRNA and protein in spinal cord astrocytes., PMID:9633805
For research use only. Not for human or drug use.
