Catalog No.
RHN23403
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Sodium channel protein type 8 subunit alpha, SCN8A, MED, Sodium channel protein type VIII subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.6
Concentration
1.61 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
K87A/10
Characterization of Sodium Channel Peptides Obtained from the Venom of the Scorpion Centruroides bonito., PMID:38535792
TNFR1 signaling converging on FGF14 controls neuronal hyperactivity and sickness behavior in experimental cerebral malaria., PMID:38115011
The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus., PMID:32569846
Super-Resolution Imaging Using a Novel High-Fidelity Antibody Reveals Close Association of the Neuronal Sodium Channel NaV1.6 with Ryanodine Receptors in Cardiac Muscle., PMID:31931893
Pathogenesis of abdominal pain in bowel obstruction: role of mechanical stress-induced upregulation of nerve growth factor in gut smooth muscle cells., PMID:28079757
Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion Centruroides limpidus., PMID:27871874
Expression of sodium channel α subunits 1.1, 1.2 and 1.6 in rat hippocampus after kainic acid-induced epilepsy., PMID:23886654
Pulpitis increases the proportion of atypical nodes of Ranvier in human dental pulp axons without a change in Nav1.6 sodium channel expression., PMID:20600647
Molecular identity of dendritic voltage-gated sodium channels., PMID:20466935
Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a., PMID:18601978
Voltage-gated sodium channel alpha-subunits Na(v)1.1, Na(v)1.2, and Na(v)1.6 in the distal mammalian retina., PMID:18079688
Expression of Nav1.1 in rat retinal AII amacrine cells., PMID:17709186
Polarized distribution of ion channels within microdomains of the axon initial segment., PMID:17111377
Localization of Na+ channel isoforms at the atrioventricular junction and atrioventricular node in the rat., PMID:16966585
Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily., PMID:16817858
Presynaptic Na+ channels: locus, development, and recovery from inactivation at a high-fidelity synapse., PMID:15814803
Molecular determinants of emerging excitability in rat embryonic motoneurons., PMID:12015418