Catalog No.
RHJ82802
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
DICER, DICER1, Helicase MOI, Endoribonuclease Dicer, Helicase with RNase motif, HERNA, KIAA0928
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N167/7
Focal High-Grade Areas with a Tumor-in-Tumor Pattern: Another Feature of Pediatric DICER1-Associated Thyroid Carcinoma?, PMID:40448797
Exomic and epigenomic analysis of pulmonary blastoma., PMID:39121796
Peptidylarginine deiminase 2 regulates expression of DGCR8 affecting miRNA biogenesis in gonadotrope cells., PMID:37310889
Immunohistochemical expression of Drosha is reduced in eutopic and ectopic endometrium of women with adenomyosis., PMID:36515351
MicroRNA and interleukin 6 interplay in the adipose tissue of rheumatoid arthritis patients., PMID:35579086
Dicer Enhances Bevacizumab-Related Inhibition of Hepatocellular Carcinoma via Blocking the Vascular Endothelial Growth Factor Pathway., PMID:35004391
Novel Insights on MRGPRX2-Mediated Hypersensitivity to Neuromuscular Blocking Agents And Fluoroquinolones., PMID:34385999
AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division., PMID:34117353
Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells., PMID:33837743
Dicer increases the indication for trastuzumab treatment in gastric cancer patients via overexpression of human epidermal growth factor receptor 2., PMID:33772068
Impaired microRNA processing in neutrophils from rheumatoid arthritis patients confers their pathogenic profile. Modulation by biological therapies., PMID:33054050
Decreased expression of miR-29 family associated with autoimmune myasthenia gravis., PMID:33032631
Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer., PMID:32847480
Nuclear re-localization of Dicer in primary mouse embryonic fibroblast nuclei following DNA damage., PMID:29394246
Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration., PMID:29323137
[Clinical Efficacy of EPOCH±R Followed by DICE±R Regimen for Primary Breast Diffuse Large B-Cell Lymphoma]., PMID:28641632
SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: a new route of epigenomic regulation., PMID:28358001
MicroRNA-375 Is Induced in Cisplatin Nephrotoxicity to Repress Hepatocyte Nuclear Factor 1-β., PMID:28119452
miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation., PMID:27880903
DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases., PMID:27808570
CRISPR/Cas9 Targets Chicken Embryonic Somatic Cells In Vitro and In Vivo and generates Phenotypic Abnormalities., PMID:27694906
Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity., PMID:27295554
Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison., PMID:27260947
The mirn23a microRNA cluster antagonizes B cell development., PMID:27084569
Dynamic distributions of long double-stranded RNA in Tetrahymena during nuclear development and genome rearrangements., PMID:26769902
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression., PMID:26725326
Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation., PMID:26421924
Sulfated galactans from Gracilaria fisheri bind to shrimp haemocyte membrane proteins and stimulate the expression of immune genes., PMID:26363236
Ablation of Dicer leads to widespread perturbation of signaling pathways., PMID:26032504
Identification of precursor microRNAs within distal axons of sensory neuron., PMID:25919946
Reduction of protein kinase C α (PKC-α) promote apoptosis via down-regulation of Dicer in bladder cancer., PMID:25752336
Requirement for CRIF1 in RNA interference and Dicer-2 stability., PMID:25483042
Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia., PMID:25405615
Downregulated expression of Dicer1 predicts inferior survival in primary gastrointestinal diffuse large B-cell lymphoma treated with CHOP-like regimen and rituximab., PMID:25195038
Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA., PMID:24814348
Coexistence of sense and anti-sense mRNAs of variant surface protein in Giardia lamblia trophozoites., PMID:24472547
Innate immunity to dengue virus infection and subversion of antiviral responses., PMID:24316047
Terminal dual-labeling of a transcribed RNA., PMID:24135725
AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression., PMID:23811941
Intersection of small RNA pathways in Arabidopsis thaliana sub-nuclear domains., PMID:23776518
Functional analysis of the RNAi response in ovary-derived silkmoth Bm5 cells., PMID:23669468
Dual functional BAFF receptor aptamers inhibit ligand-induced proliferation and deliver siRNAs to NHL cells., PMID:23470998
Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma., PMID:23370771
Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients., PMID:23266047
Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing., PMID:22810205
The RNA binding protein SAM68 transiently localizes in the chromatoid body of male germ cells and influences expression of select microRNAs., PMID:22745822
The microRNA-processing enzyme Dicer is essential for thyroid function., PMID:22132122
The RNase III enzyme Dicer is essential for germinal center B-cell formation., PMID:22117047
High expression of Dicer reveals a negative prognostic influence in certain subtypes of primary cutaneous T cell lymphomas., PMID:21937200
Dicer-substrate siRNA inhibits tumor necrosis factor alpha secretion in Kupffer cells in vitro: in vivo targeting of Kupffer cells by siRNA-liposomes., PMID:21933712
For research use only. Not for human or drug use.
