Catalog No.
RHN22401
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
hTRP-5, TRP-5, Transient receptor protein 5, Short transient receptor potential channel 5, hTRP5, TRP5, TrpC5, TRPC5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N67/15
HC070, a Transient Receptor Potential Canonical 5 (TRPC5) Channels Inhibitor Ameliorated α-synuclein Preformed Fibrils-Induced Parkinson's Disease: A Neurobehavioural and Mechanistic Study., PMID:40066713
Direct modulation of TRPC ion channels by Gα proteins., PMID:38384797
Immunohistochemistry Reveals TRPC Channels in the Human Hearing Organ-A Novel CT-Guided Approach to the Cochlea., PMID:37298241
Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ into Neurons., PMID:36077460
PACAP Induces Light Aversion in Mice by an Inheritable Mechanism Independent of CGRP., PMID:33846231
Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells., PMID:32033274
Plasma membrane mechanical stress activates TRPC5 channels., PMID:25849346
The role of canonical transient receptor potential channels in seizure and excitotoxicity., PMID:24722470
Tumor endothelial expression of P-glycoprotein upon microvesicular transfer of TrpC5 derived from adriamycin-resistant breast cancer cells., PMID:24582564
Expression and localization of TRPC proteins in rat ventricular myocytes at various developmental stages., PMID:24146259
Persistent histamine excitation of glutamatergic preoptic neurons., PMID:23082195
Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors., PMID:22699894
Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin., PMID:22668831
TRP channel gene expression in the mouse retina., PMID:22037305
Activation of TRPC cationic channels by mercurial compounds confers the cytotoxicity of mercury exposure., PMID:21984481
TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1-/- mice., PMID:21968068
Cholecystokinin facilitates neuronal excitability in the entorhinal cortex via activation of TRPC-like channels., PMID:21753024
Rat hypocretin/orexin neurons are maintained in a depolarized state by TRPC channels., PMID:21179559
TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca2+- and PKC-dependent mechanism in native vascular myocytes., PMID:20660561
Stretch-activated cation channel from larval bullfrog skin., PMID:20435829
Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells., PMID:20390293
Short-term stimulation of calcium-permeable transient receptor potential canonical 5-containing channels by oxidized phospholipids., PMID:20378846
Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP3 and PIP2 in rabbit coronary artery myocytes., PMID:19770190
Increased rhythmicity in hypertensive arterial smooth muscle is linked to transient receptor potential canonical channels., PMID:19725917
The specific activation of TRPC4 by Gi protein subtype., PMID:18854172
Production of a specific extracellular inhibitor of TRPM3 channels., PMID:18604232
Transient receptor potential cation channels in normal and dystrophic mdx muscle., PMID:18504127
Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes., PMID:18356201
Ca2+ entry through TRPC1 channels contributes to intracellular Ca2+ dynamics and consequent glutamate release from rat astrocytes., PMID:18338793
High glucose enhances transient receptor potential channel canonical type 6-dependent calcium influx in human platelets via phosphatidylinositol 3-kinase-dependent pathway., PMID:18258814
Immunohistochemical study on the distribution of canonical transient receptor potential channels in rat basal ganglia., PMID:17590510
Store-operated Ca2+ influx and expression of TRPC genes in mouse sinoatrial node., PMID:17478725
E3-targeted anti-TRPC5 antibody inhibits store-operated calcium entry in freshly isolated pial arterioles., PMID:16861696
A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility., PMID:16675717
Immunohistochemical study on the distribution of TRPC channels in the rat hippocampus., PMID:16580647
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells., PMID:16418302
Synaptic activation of transient receptor potential channels by metabotropic glutamate receptors in the lateral amygdala., PMID:16289832
Ca2+-calmodulin-dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells., PMID:16284075
Transient receptor potential protein subunit assembly and membrane distribution in human platelets., PMID:16270640
Generation of functional ion-channel tools by E3 targeting., PMID:16170312
Distribution of TRPC1 and TRPC5 in medial temporal lobe structures of mice., PMID:16044320
Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase., PMID:16025302
Association of immunophilins with mammalian TRPC channels., PMID:15199065
Distribution of transient receptor potential channels in the rat carotid chemosensory pathway., PMID:12900933
Evidence for the expression of transient receptor potential proteins in guinea pig airway smooth muscle cells., PMID:12856738
TRPC1 store-operated cationic channel subunit., PMID:12765688
TRPC5 as a candidate for the nonselective cation channel activated by muscarinic stimulation in murine stomach., PMID:12631560
For research use only. Not for human or drug use.
