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Anti-IL24 Polyclonal Antibody

Catalog #:   PHG37001 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q13007
Overview

Catalog No.

PHG37001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IL24 (Gln52-Leu206).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

MDA7,MDA-7,ST16,IL-24,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein,IL24,Interleukin-24

Purification

Purified by antigen affinity column.

Accession

Q13007

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IL24 antibody (PHG37001) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 20 kDa
    Observed MW: 20 kDa
  • Immunocytochemistry/ Immunofluorescence
    IL24 in Hela Cell Line.
    The Hela cells were fixed with 4% paraformaldehyde (20 min), and then blocked with 5% goat serum for 1h. And the cells were incubated for 2h at 37°C with IL24 (PHG37001) at 4.5 μg/ml. The section was then incubated with Goat Anti-Rabbit IgG (Alexa Fluor-594) preabsorbed at 1/100 dilution (Shown in red) for 1 hour at room temperature.Nuclear DNA was labelled with DAPI (shown in blue).
References

Advances of oncolytic vaccinia viruses armed with interleukin in tumor therapy., PMID:40469178

RNase 7 and Th cytokines synergistically increase the secretion of interleukin-6 from keratinocytes., PMID:40461723

Unraveling the role of the IL-20 cytokine family in neurodegenerative diseases: Mechanisms and therapeutic insights., PMID:40068518

Advancements and challenges in immunocytokines: A new arsenal against cancer., PMID:39664443

IgG autoantibodies in bullous pemphigoid directly induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes., PMID:39569141

The levels of circulating cytokines and risk of neuromyelitis optica spectrum disorder: a Mendelian randomization study., PMID:39011048

CD200R activation on naïve T cells by B cells induces suppressive activity of T cells via IL-24., PMID:38780647

Early B cell transcriptomic markers of measles-specific humoral immunity following a 3rd dose of MMR vaccine., PMID:38633249

The role of IL-19, IL-24, IL-21 and IL-33 in intestinal mucosa of inflammatory bowel disease: A narrative review., PMID:38395629

Spinal interleukin-24 contributes to neuropathic pain after peripheral nerve injury through interleukin-20 receptor2 in mice., PMID:38056582

Protective role of IL-17-producing γδ T cells in a laser-induced choroidal neovascularization mouse model., PMID:38007487

In silico investigation of a novel anti-EGFR scFv-IL-24 fusion protein induces apoptosis in malignant cells., PMID:37606822

IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37., PMID:36174993

Autoimmune chronic spontaneous urticaria., PMID:35667749

Interleukin-17A Drives IL-19 and IL-24 Expression in Skin Stromal Cells Regulating Keratinocyte Proliferation., PMID:34616394

Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab: A study protocol., PMID:32957324

Identification of antigenic epitopes of thyroperoxidase, thyroglobulin and interleukin-24. Exploration of cross-reactivity with environmental allergens and possible role in urticaria and hypothyroidism., PMID:32027873

Inhibition of NR4A1 Promotes ROS Accumulation and IL24-Dependent Growth Arrest in Rhabdomyosarcoma., PMID:31462501

[Recent progress in the pathophysiological role of interleukin-19]., PMID:31406045

IL-20-Receptor Signaling Delimits IL-17 Production in Psoriatic Inflammation., PMID:31252033

Immunological effects and potential mechanisms of action of autologous serum therapy in chronic spontaneous urticaria., PMID:31025425

Increased expression of IL-24 in chronic spontaneous urticaria., PMID:31006117

HIV-1 infection modulates IL-24 expression which contributes to cell apoptosis in vitro., PMID:30761646

IL-24 contributes to skin inflammation in Para-Phenylenediamine-induced contact hypersensitivity., PMID:30755657

Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae., PMID:30361066

The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis., PMID:30319661

Immunoglobulin E-Mediated Autoimmunity., PMID:29686678

Iron-induced calcification in human aortic vascular smooth muscle cells through interleukin-24 (IL-24), with/without TNF-alpha., PMID:29330517

IL-24 is a common and specific autoantigen of IgE in patients with chronic spontaneous urticaria., PMID:29208545

Perinatal exposure to tetrabromobisphenol A (TBBPA), a brominated flame retardant, exacerbated the pneumonia in respiratory syncytial virus (RSV)-infected offspring mice., PMID:29142177

Limited Presence of IL-22 Binding Protein, a Natural IL-22 Inhibitor, Strengthens Psoriatic Skin Inflammation., PMID:28356382

IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas., PMID:28330899

IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice., PMID:28125663

Oncolytic Adenovirus Complexes Coated with Lipids and Calcium Phosphate for Cancer Gene Therapy., PMID:27977128

Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression., PMID:27807832

Macrophages promote the growth and invasion of endometrial stromal cells by downregulating IL-24 in endometriosis., PMID:27624484

A Broad Blockade of Signaling from the IL-20 Family of Cytokines Potently Attenuates Collagen-Induced Arthritis., PMID:27619991

An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells., PMID:27528029

Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer., PMID:27349517

The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression., PMID:26968800

Therapeutic implication of genetic variants of IL13 and STAT4 in airway remodelling with bronchial asthma., PMID:26765219

Inhibition of the Aurora A kinase augments the anti-tumor efficacy of oncolytic measles virotherapy., PMID:26272026

Cytokine-induced killer cells combined with dendritic cells inhibited liver cancer cells., PMID:26131143

Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activity., PMID:26009991

A novel human interleukin-24 peptide created by computer-guided design contributes to suppression of proliferation in esophageal squamous cell carcinoma Eca-109 cells., PMID:25371158

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress., PMID:25362253

Molecular targets and signaling pathways regulated by interleukin (IL)-24 in mediating its antitumor activities., PMID:24377906

Gene expression profiling of the leading edge of cutaneous squamous cell carcinoma: IL-24-driven MMP-7., PMID:24270662

Sigma 1 Receptor plays a prominent role in IL-24-induced cancer-specific apoptosis., PMID:23988449

A simple set of validation steps identifies and removes false results in a sandwich enzyme-linked immunosorbent assay caused by anti-animal IgG antibodies in plasma from arthritis patients., PMID:23875127

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-IL24 Polyclonal Antibody [PHG37001]
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