Catalog No.
RHN18902
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
hSMURF1, E3 ubiquitin-protein ligase SMURF1, HECT-type E3 ubiquitin transferase SMURF1, KIAA1625, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1, SMURF1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
L12/33
NDRG1 enhances the sensitivity to Cetuximab by promoting Stat1 ubiquitylation in colorectal cancer., PMID:39128702
SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis., PMID:37994046
cMet agonistic antibody prevents acute kidney injury to chronic kidney disease transition by suppressing Smurf1 and activating Smad7., PMID:34061176
Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities., PMID:33480423
Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance., PMID:31623230
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Bone morphogenic protein-2 regulates the myogenic differentiation of PMVECs in CBDL rat serum-induced pulmonary microvascular remodeling., PMID:26071935
ATR/Chk1/Smurf1 pathway determines cell fate after DNA damage by controlling RhoB abundance., PMID:25249323
Inhibition of rhBMP-2-induced ALP activity by intracellular delivery of SMURF1 in murine calvarial preosteoblast cells., PMID:24288199
Immunolocalization of Smurf1 in Hirano bodies., PMID:24238996
Up-regulation of Smurf1 after spinal cord injury in adult rats., PMID:23595775
TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity., PMID:21791611
Opposing effects of Arkadia and Smurf on TGFbeta1-induced IgA isotype expression., PMID:17978583
Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation., PMID:16959829
Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis., PMID:16917513
For research use only. Not for human or drug use.
