Catalog No.
RHN17702
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
TRPML1, Mucolipidin, Mucolipin-1, MG-2, MCOLN1, ML1, Transient receptor potential channel mucolipin 1, ML4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N267/5
Whole-body analysis of TRPML3 (MCOLN3) expression using a GFP-reporter mouse model reveals widespread expression in secretory cells and endocrine glands., PMID:36520788
The intracellular Ca2+ release channel TRPML1 regulates lower urinary tract smooth muscle contractility., PMID:33199609
BK Channels Alleviate Lysosomal Storage Diseases by Providing Positive Feedback Regulation of Lysosomal Ca2+ Release., PMID:25982675
TRP channel gene expression in the mouse retina., PMID:22037305
TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes., PMID:18754814
Reconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of rats., PMID:17613490
Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes., PMID:16497227
Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV., PMID:11013137