Anti-TrpM7 Antibody (N74/25)

Catalog No.

RHK83403

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

LTrpC7, LTRPC7, LTrpC-7, TRPM7, Transient receptor potential cation channel subfamily M member 7, CHAK1, Long transient receptor potential channel 7, Channel-kinase 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N74/25

TRPM6 in murine kidneys-of targets and antibodies., PMID:40025338

Cardiovascular toxicity of tyrosine kinase inhibitors during cancer treatment: Potential involvement of TRPM7., PMID:36818331

Evidence for the expression of TRPM6 and TRPM7 in cardiomyocytes from all four chamber walls of the human heart., PMID:34326388

The channel-kinase TRPM7 regulates antigen gathering and internalization in B cells., PMID:29871912

Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry., PMID:29445164

Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation., PMID:29343440

Hepatocellular differentiation status is characterized by distinct subnuclear localization and form of the chanzyme TRPM7., PMID:28609676

Effects of TRPM7/miR-34a Gene Silencing on Spatial Cognitive Function and Hippocampal Neurogenesis in Mice with Type 1 Diabetes Mellitus., PMID:28185128

TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma., PMID:27629139

Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle., PMID:25820697

TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways., PMID:25192910

Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C γ2 (PLCγ2) using TRPM7-kinase., PMID:22759789

Identification of the phosphorylation sites on intact TRPM7 channels from mammalian cells., PMID:22222377

TRP channel gene expression in the mouse retina., PMID:22037305

TRP expression pattern and the functional importance of TRPC3 in primary human T-cells., PMID:21215279

Functional characterization of transient receptor potential channels in mouse urothelial cells., PMID:20015940

Modulation of TRPM6 and Na(+)/Mg(2+) exchange in mammary epithelial cells in response to variations of magnesium availability., PMID:19890837

Regulation of the novel Mg2+ transporter transient receptor potential melastatin 7 (TRPM7) cation channel by bradykinin in vascular smooth muscle cells., PMID:19145781

[Transient receptor potential melastatin 7 channel protein in human head and neck carcinoma cells and role in cell proliferation]., PMID:18826101

Transient receptor potential cation channels in normal and dystrophic mdx muscle., PMID:18504127

The channel kinases TRPM6 and TRPM7 are functionally nonredundant., PMID:16150690

A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders., PMID:16051700

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Anti-TrpM7 Antibody (N74/25).pdf