Catalog No.
RHN12601
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
NLGN1, Neuroligin-1, KIAA1070
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N97A/31
High-affinity detection of biotinylated endogenous neuroligin-1 at excitatory and inhibitory synapses using a tagged knock-in mouse., PMID:40424132
Neuroligin1 in excitatory synapses contributes to long-term cognitive impairments after repeated neonatal sevoflurane exposures., PMID:38493982
Glyoxal fixation: An approach to solve immunohistochemical problem in neuroscience research., PMID:37450597
Epitope-tag-mediated synaptogenic activity in an engineered neurexin-1β lacking the binding interface with neuroligin-1., PMID:37030069
Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia., PMID:37004758
Tumoral Neuroligin 1 Promotes Cancer-Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor., PMID:35053395
Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice., PMID:34882968
Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation., PMID:31754030
Cellular and Subcellular Localization of Endogenous Neuroligin-1 in the Cerebellum., PMID:30046996
NLGN1 and NLGN2 in the prefrontal cortex: their role in memory consolidation and strengthening., PMID:29278843
Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice., PMID:28283575
Release activity-dependent control of vesicle endocytosis by the synaptic adhesion molecule N-cadherin., PMID:28106089
Assembly of synapses: biomimetic assays to control neurexin/neuroligin interactions at the neuronal surface., PMID:23853109
Neurexin-1β binding to neuroligin-1 triggers the preferential recruitment of PSD-95 versus gephyrin through tyrosine phosphorylation of neuroligin-1., PMID:23770246
MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development., PMID:23248271
The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions., PMID:19926856
Selegiline is an efficient and potent inducer for bone marrow stromal cell differentiation into neuronal phenotype., PMID:19422735
Apolipoprotein E4 domain interaction: synaptic and cognitive deficits in mice., PMID:18631967
Adhesion molecules in the nervous system: structural insights into function and diversity., PMID:17600523
Molecular reconstitution of functional GABAergic synapses with expression of neuroligin-2 and GABAA receptors., PMID:17336090
Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism., PMID:15797875
The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing., PMID:15152050
A stoichiometric complex of neurexins and dystroglycan in brain., PMID:11470830
Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses., PMID:9927700
For research use only. Not for human or drug use.
