Catalog No.
PHG07701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human REG3A (Cys40-Asn164).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Regenerating islet-derived protein 3-alpha,PAP1,Regenerating islet-derived protein III-alpha,Hepatointestinal pancreatic protein,REG-3-alpha,HIP,REG3A,Pancreatitis-associated protein 1,Human proislet peptide,PAP,HIP/PAP,Reg III-alpha
Purification
Purified by antigen affinity column.
Accession
Q06141
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Hemolymph protease-17b activates proHP6 to stimulate melanization and Toll signaling in Manduca sexta., PMID:39406299
Reg3A Overexpression Facilitates Hepatic Metastasis by Altering Cell Adhesion in LoVo Colon Cancer Cells., PMID:38771249
Identification of regenerating island-derived protein 3E in dogs., PMID:36387376
Myocardial Accumulations of Reg3A, Reg3γ and Oncostatin M Are Associated with the Formation of Granulomata in Patients with Cardiac Sarcoidosis., PMID:33923774
P. gingivalis Lipopolysaccharide Stimulates the Upregulated Expression of the Pancreatic Cancer-Related Genes Regenerating Islet-Derived 3 A/G in Mouse Pancreas., PMID:33027970
Anti-tumor effect of single-chain antibody to Reg3a in colorectal cancer., PMID:32918897
Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL-22Fc): A Potential Therapy for Epithelial Injury., PMID:29952004
Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases., PMID:29608910
Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk., PMID:26646797
IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer., PMID:26404002
Identification of the major regenerative III protein (RegIII) in the porcine intestinal mucosa as RegIIIγ, not RegIIIα., PMID:26187439
The Reg3α (HIP/PAP) Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure., PMID:25938566
Islet neogenesis-associated protein (INGAP): the role of its endogenous production as a positive modulator of insulin secretion., PMID:25160856
iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance., PMID:23579209
N-terminal cleaved pancreatitis-associated protein-III (PAP-III) serves as a scaffold for neurites and promotes neurite outgrowth., PMID:23426365
A cell free assay system estimating the neutralizing capacity of GM-CSF antibody using recombinant soluble GM-CSF receptor., PMID:21730949
Expression profile of the REG gene family in colorectal carcinoma., PMID:21339177
Human hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein cures fas-induced acute liver failure in mice by attenuating free-radical damage in injured livers., PMID:21274882
Manduca sexta serpin-5 regulates prophenoloxidase activation and the Toll signaling pathway by inhibiting hemolymph proteinase HP6., PMID:20624461
Islet neogenesis-associated protein-related pentadecapeptide enhances the differentiation of islet-like clusters from human pancreatic duct cells., PMID:19747955
Selective effect of INGAP-PP upon mouse embryonic stem cell differentiation toward islet cells., PMID:19159649
Microarray analysis of somatostatin receptor 5-regulated gene expression profiles in murine pancreas., PMID:19137362
Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function., PMID:18281463
Pancreatic islet immunoreactivity to the Reg protein INGAP., PMID:17998566
Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques., PMID:17959847
Intramuscular injection of islet neogenesis-associated protein peptide stimulates pancreatic islet neogenesis in healthy dogs., PMID:17198191
Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice., PMID:17133485
Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development., PMID:16837177
PDX-1 can repress stimulus-induced activation of the INGAP promoter., PMID:16522740
Effect of nitrosative stress on Schizosaccharomyces pombe: inactivation of glutathione reductase by peroxynitrite., PMID:16458193
Molecular identification of a bevy of serine proteinases in Manduca sexta hemolymph., PMID:15944088
Expression of Reg/PAP family members during motor nerve regeneration in rat., PMID:15896308
Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide., PMID:15824112
A comprehensive approach for establishment of the platform to analyze functions of KIAA proteins II: public release of inaugural version of InGaP database containing gene/protein expression profiles for 127 mouse KIAA genes/proteins., PMID:15500254
PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor., PMID:15474994
Amelioration of the beta-cell dysfunction in diabetic APA hamsters by antioxidants and AGE inhibitor treatments., PMID:15133752
Negative regulation of prophenoloxidase (proPO) activation by a clip-domain serine proteinase homolog (SPH) from endoparasitoid venom., PMID:15110869
Purification and characterization of Manduca sexta serpin-6: a serine proteinase inhibitor that selectively inhibits prophenoloxidase-activating proteinase-3., PMID:15041022
Identification of pro-interleukin 16 as a novel target of MAP kinases in activated T lymphocytes., PMID:14768064
p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I., PMID:14660681
Pancreatic changes in TNBS-induced colitis in mice., PMID:14631304
Pancreatic duodenal homeobox-1 and islet neogenesis-associated protein: a possible combined marker of activateable pancreatic cell precursors., PMID:12740013
Expression of islet neogenesis-associated protein in islets of normal hamsters., PMID:12740012
The pancreatitis-associated protein induces lung inflammation in the rat through activation of TNFalpha expression in hepatocytes., PMID:12579542
Approaches to define antigen receptor-induced serine kinase signal transduction pathways., PMID:12515807
Possible relationship between changes in islet neogenesis and islet neogenesis-associated protein-positive cell mass induced by sucrose administration to normal hamsters., PMID:10828857
Inducible transcription factor expression in a cell culture model of apoptosis., PMID:10095097
Synthetic lethal interactions with conditional poly(A) polymerase alleles identify LCP5, a gene involved in 18S rRNA maturation., PMID:9814757
Establishment and immunocharacterization of an immortalized pancreatic cell line derived from the H-2Kb-tsA58 transgenic mouse., PMID:9358288
Pancreatitis-associated protein: a putative marker for pancreas graft rejection., PMID:9112354
For research use only. Not for human or drug use.
