Catalog No.
RHK15401
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
LTrpC6, TRPP8, LTRPC6, Transient receptor potential cation channel subfamily M member 8, Transient receptor potential p8, TRPM8, LTrpC-6, Trp-p8, Long transient receptor potential channel 6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N198/17
TRPM8 levels determine tumor vulnerability to channel agonists., PMID:40405392
Implication of TRPM8, CD47, and CDK4 expressions in hepatocellular carcinoma progression., PMID:39957041
Optimization and calibration of 384-well kinetic Ca2+ mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1., PMID:39746519
The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8., PMID:39552306
The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8., PMID:39314341
Targeting Grancalcin Accelerates Wound Healing by Improving Angiogenesis in Diabetes., PMID:38308197
Transient receptor potential ankyrin 1 (TRPA1) and transient receptor potential melastatin 8 (TRPM8) in human odontoblast-like cells participate in lipopolysaccharide-induced immune response., PMID:37683373
Validation of Six Commercial Antibodies for the Detection of Heterologous and Endogenous TRPM8 Ion Channel Expression., PMID:36555804
ELTD1 as a multi-focal target for malignant gliomas: preclinical studies., PMID:34704036
Identification of Trigeminal Sensory Neuronal Types Innervating Masseter Muscle., PMID:34580157
TRPM8 protein expression in hormone naïve local and lymph node metastatic prostate cancer., PMID:33955429
Effects of activation of skin ion channels TRPM8, TRPV1, and TRPA1 on the immune response. Comparison with effects of cold and heat exposure., PMID:33077140
TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3., PMID:32863706
Exposure to formaldehyde at low temperatures aggravates allergic asthma involved in transient receptor potential ion channel., PMID:32798733
TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3., PMID:38860239
3'-O-Methylorobol Inhibits the Voltage-Gated Sodium Channel Nav1.7 with Anti-Itch Efficacy in A Histamine-Dependent Itch Mouse Model., PMID:31805638
The role of urea in neuronal degeneration and sensitization: An in vitro model of uremic neuropathy., PMID:31549574
TRPM8-mediated cutaneous stimulation modulates motor neuron activity during treadmill stepping in mice., PMID:31482469
Remodeling of Substance P Sensory Nerves and Transient Receptor Potential Melastatin 8 (TRPM8) Cold Receptors After Corneal Experimental Surgery., PMID:31157834
TRPM8 channel inhibitor AMTB suppresses murine T-cell activation induced by T-cell receptor stimulation, concanavalin A, or external antigen re-stimulation., PMID:30642628
The Effects of Diabetes and High-Fat Diet on Polymodal Nociceptor and Cold Thermoreceptor Nerve Terminal Endings in the Corneal Epithelium., PMID:30641549
Lacrimal Gland Denervation Alters Tear Protein Composition and Impairs Ipsilateral Eye Closures and Corneal Nociception., PMID:30372750
Porcine FcεRI Mediates Porcine Reproductive and Respiratory Syndrome Virus Multiplication and Regulates the Inflammatory Reaction., PMID:29761267
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus., PMID:29635321
The identification of the TRPM8 channel on primary culture of human nasal epithelial cells and its response to cooling., PMID:28767579
Transient receptor potential melastatin (TRPM) 8 is expressed in freshly isolated native human odontoblasts., PMID:28043013
Localization and expression patterns of TRP channels in submandibular gland development., PMID:27875791
Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice., PMID:27812120
Expression of temperature-sensitive ion channel TRPM8 in sperm cells correlates with vertebrate evolution., PMID:26500819
Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype., PMID:26496712
Pilot study to determine whether transient receptor potential melastatin type 8 (TRPM8) antibodies are detected in scleroderma., PMID:26242276
TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells., PMID:25980497
Antibodies to the extracellular pore loop of TRPM8 act as antagonists of channel activation., PMID:25203266
Targeting TRP channels for novel migraine therapeutics., PMID:25138211
Ion channel TRPM8 promotes hypoxic growth of prostate cancer cells via an O2 -independent and RACK1-mediated mechanism of HIF-1α stabilization., PMID:25065497
Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats., PMID:24996127
TRPM8 promotes aggressiveness of breast cancer cells by regulating EMT via activating AKT/GSK-3β pathway., PMID:24903376
The distribution of transient receptor potential melastatin-8 in the rat soft palate, epiglottis, and pharynx., PMID:23132652
Human odontoblasts express functional thermo-sensitive TRP channels: implications for dentin sensitivity., PMID:21168271
Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer., PMID:20682256
Expression of transient receptor potential channel vanilloid (TRPV) 1–4, melastin (TRPM) 5 and 8, and ankyrin (TRPA1) in the normal and methimazole-treated mouse olfactory epithelium., PMID:20586674
AFM imaging reveals the tetrameric structure of the TRPM8 channel., PMID:20214891
Functional characterization of transient receptor potential channels in mouse urothelial cells., PMID:20015940
TRPM8, a versatile channel in human sperm., PMID:19582168
Neuropathic pain: emerging treatments., PMID:18511441
TRPM8 Axonal expression is decreased in painful human teeth with irreversible pulpitis and cold hyperalgesia., PMID:17889683
TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi., PMID:17142461
Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate., PMID:17074062
Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations., PMID:16519806
TRPM8 protein localization in trigeminal ganglion and taste papillae., PMID:15893591
For research use only. Not for human or drug use.
