Catalog No.
RHN25603
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
27 kDa inositol polyphosphate phosphatase interacting protein B, Ses2, IPIP27B, PH domain-containing endocytic trafficking adaptor 2, Sesquipedalian-2, PHETA2, FAM109B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N166A/8
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
Imaging of Intracellular and Plasma Membrane Pools of PI(4,5)P2 and PI4P in Human Platelets., PMID:34947862
Study of methylation of histone H3 lysine 9 and H3 lysine 27 during X chromosome inactivation in three types of cells., PMID:22956184
Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)P₂ and membrane scission., PMID:22341461
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1., PMID:21378754
Relationship between spleen tyrosine kinase and phosphatidylinositol 5' phosphatase expression and secretion from human basophils in the general population., PMID:17336612
Lowe syndrome protein Ocrl1 is translocated to membrane ruffles upon Rac GTPase activation: a new perspective on Lowe syndrome pathophysiology., PMID:15829501
The deficiency of PIP2 5-phosphatase in Lowe syndrome affects actin polymerization., PMID:12428211
Ocrl1, a PtdIns(4,5)P(2) 5-phosphatase, is localized to the trans-Golgi network of fibroblasts and epithelial cells., PMID:10639484
Novel inositol polyphosphate 5-phosphatase localizes at membrane ruffles., PMID:10593988
Identification and characterization of golgin-84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain., PMID:9915833
Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate., PMID:9430698
The oculocerebrorenal syndrome gene product is a 105-kD protein localized to the Golgi complex., PMID:7573041
For research use only. Not for human or drug use.
