Anti-CLC Polyclonal Antibody

Catalog No.

PHG04501

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CLC (Ser2-Arg142).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Lysolecithin acylhydrolase,Galectin-10,LGALS10A,CLC,Gal-10,LGALS10,Eosinophil lysophospholipase,Charcot-Leyden crystal protein

Purification

Purified by antigen affinity column.

Accession

Q05315

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Effect of probiotics on immune cells in young Japanese Black calves responding to vaccination against bacterial respiratory diseases., PMID:40144064

Canakinumab Treatment in Familial Mediterranean Fever Patients: With/Without Colchicine., PMID:40040547

A Cftr-independent, Ano1-rich seawater-adaptive ionocyte in sea lamprey gills., PMID:40007443

Proliferative retinopathy in a patient with mutation in the CLCN2 gene., PMID:39980384

Five-Year (2017-2022) Evolutionary Dynamics of Human Coronavirus HKU1 in Southern France With Emergence of Viruses Harboring Spike H512R Substitution., PMID:39949218

Identification and Validation of B-Cell Epitopes on the VP1 Protein of Parvovirus B19 through Molecular Docking and Dynamics Simulation., PMID:39926541

Discovery of a common light chain bispecific antibody targeting PD-1 and PD-L1 by Hybridoma-to-Phage-to-Yeast (H2PtY) platform., PMID:39839911

Elevated MS4A2 and IgE interaction in nasal polyps contributing to poor postoperative prognosis in patients with eosinophilic chronic rhinosinusitis., PMID:39828458

Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost., PMID:39824819

Risankizumab efficacy and safety based on prior inadequate response or intolerance to advanced therapy: post hoc analysis of the INSPIRE and COMMAND phase 3 studies., PMID:39804294

An antibody cocktail targeting two different CD73 epitopes enhances enzyme inhibition and tumor control., PMID:39738003

Conformational Differences in the Light Chain Constant Domain of Immunoglobulin G and Free Light Chain May Influence Proteolysis in AL Amyloidosis., PMID:39490919

The impact of Charcot-Leyden Crystal protein on mesothelioma chemotherapy: targeting eosinophils for enhanced chemosensitivity., PMID:39471751

B cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort., PMID:39417147

Microfluidic Affinity Selection of B-Lineage Cells from Peripheral Blood for Minimal Residual Disease Monitoring in Pediatric B-Type Acute Lymphoblastic Leukemia Patients., PMID:39408948

Generation of Antibody Libraries for Phage Display: Chimeric Rabbit/Human Fab Format., PMID:39406531

Generation of Antibody Libraries for Phage Display: Human Fab Format., PMID:39406530

Targeted recruitment of immune effector cells for rapid eradication of influenza virus infections., PMID:39348541

Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial., PMID:39325506

Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 trial., PMID:39288779

Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma., PMID:39282897

Association of Combined Autoreactivity to Sm/RNP Common Motif and U1 RNP With Mixed Connective Tissue Disease and Systemic Lupus Erythematosus., PMID:39270208

Maternal Immunization with Adjuvanted Recombinant Receptor-Binding Domain Protein Provides Immune Protection against SARS-CoV-2 in Infant Monkeys., PMID:39204052

Embryonic, Fetal, and Neonatal Complications in Infants of Diabetic Mothers: Insights from the Cincinnati Diabetes in Pregnancy Program Project Grant., PMID:39117332

T-cell Mediated Rejection Associated Microvascular Inflammation in the Allograft Kidney: RNAseq Analysis Using the Banff Human Organ Transplant Gene Panel., PMID:39033507

Combination Targeted Therapy with Pembrolizumab and Lenvatinib in Progressive, Radioiodine-Refractory Differentiated Thyroid Cancers., PMID:38922338

Recombinant Alpha-1 Antitrypsin-Fc Fusion Protein INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency: A Phase 1 Study., PMID:38809792

A Single Centre Experience of Effective Desensitization Strategy for Children with High Anti-HLA Donor-Specific Antibodies Undergoing Haploidentical Hematopoietic Stem Cell Transplantation., PMID:38708152

Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice., PMID:38666049

Global and single-nucleotide resolution detection of 7-methylguanosine in RNA., PMID:38566310

Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial., PMID:38521086

Validation and shortcomings of the most common mouse model of chronic rhinosinusitis with nasal polyps., PMID:38497676

Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager., PMID:38474651

Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study., PMID:38246194

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies., PMID:38236959

Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation., PMID:38147543

Safety, Tolerability, and Immunogenicity of Booster Dose with MVC-COV1901 or MVC-COV1901-Beta SARS-CoV-2 Vaccine in Adults: A Phase I, Prospective, Randomized, Open-Labeled Study., PMID:38140202

NULISA: a proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing., PMID:37945559

Immuno-profiling of Brucella proteins for developing improved vaccines and DIVA capable serodiagnostic assays for brucellosis., PMID:37860136

Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particles., PMID:37803013

Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial., PMID:37783970

SARS-CoV-2 infection and long COVID among California farmworkers., PMID:37715721

Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial., PMID:37640860

Kappa Free Light Chain Index Predicts Disease Course in Clinically and Radiologically Isolated Syndromes., PMID:37640543

Cancer Risk Following HLA-Incompatible Living Donor Kidney Transplantation., PMID:37492080

Bivalent and Monovalent SARS-CoV-2 Variant Vaccine Boosters Improve coverage of the known Antigenic Landscape: Results of the COVID-19 Variant Immunologic Landscape (COVAIL) Trial., PMID:37205592

Generation of Synthetic Acinetobacter baumannii-Specific Nanobodies., PMID:37162304

Generation of B-cell-based cellular vaccine for cancer in murine models., PMID:37083319

Single priming and booster dose of ten-valent and 13-valent pneumococcal conjugate vaccines and Streptococcus pneumoniae colonisation in children in South Africa: a single-centre, open-label, randomised trial., PMID:36934731

Immune correlates analysis of a phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine., PMID:36899062

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