Catalog No.
PHG01001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RELA (Met1-Gln220).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,RELA,Transcription factor p65,NFKB3
Concentration
0.58 mg/ml
Purification
Purified by antigen affinity column.
Accession
Q04206
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Neferine inhibits PRRSV infection by disrupting p65 nuclear translocation., PMID:40311944
Human papilloma virus vaccine induced Kikuchi-Fujimoto disease: A case report., PMID:40296399
Inhibiting the Translocation of HMGB1 Alleviates Renal Ischemia-Reperfusion Injury by Cutting Down Inflammatory Cascade., PMID:40107932
Citrullination of NF-κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury., PMID:40087815
A case of assisted reproductive technology-induced maternal alloimmunization: an emerging sensitizing factor to consider?, PMID:39740010
Nivolumab plus relatlimab and nivolumab plus ipilimumab for patients with advanced renal cell carcinoma: results from the open-label, randomised, phase II FRACTION-RCC trial., PMID:39642635
NF-ΚB Activation as a Key Driver in Chronic Lymphocytic Leukemia Evolution to Richter's Syndrome: Unraveling the Influence of Immune Microenvironment Dynamics., PMID:39596634
Chromatin remodelling drives immune cell-fibroblast communication in heart failure., PMID:39443808
Real-world treatment patterns and outcomes of patients with advanced melanoma treated with nivolumab plus relatlimab., PMID:39293068
A First-in-Human Study of Cinrebafusp Alfa, a HER2/4-1BB Bispecific Molecule, in Patients with HER2-Positive Advanced Solid Malignancies., PMID:39235868
Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity., PMID:39121849
The effects of mineral trioxide aggregate and second-generation autologous growth factor on pulpotomy via TNF-α and NF-kβ/p65 pathways., PMID:39097700
DLK1 regulates periodontal inflammation by inhibiting NF-κB p65 and JNK signaling pathways., PMID:38995322
Coexistence of systemic sclerosis and cryopyrin-associated periodic syndrome., PMID:38940218
Expression and significance of Fractalkine/CX3CL1 in MPO-AAV-associated glomerulonephritis rats., PMID:38937701
Exploration of the Shared Gene Signatures and Molecular Mechanisms between Chronic Bronchitis and Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis: Evidence from Transcriptome Data., PMID:38847168
Characterization of Potential Target Genes of Borneol in Increasing Trastuzumab Sensitivity in HER2+ Trastuzumab-Resistant Breast Cancer: Bioinformatics and In Vitro Studies., PMID:38809634
A Single Centre Experience of Effective Desensitization Strategy for Children with High Anti-HLA Donor-Specific Antibodies Undergoing Haploidentical Hematopoietic Stem Cell Transplantation., PMID:38708152
Yiqi Kaimi prescription regulates protein phosphorylation to promote intestinal motility in slow transit constipation., PMID:38614261
Exploring personalized treatment for cardiac graft rejection based on a four-archetype analysis model and bioinformatics analysis., PMID:38499711
IL-10 Differentially Promotes Mast Cell Responsiveness to IL-33, Resulting in Enhancement of Type 2 Inflammation and Suppression of Neutrophilia., PMID:38497670
TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer., PMID:38104742
Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab-bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study., PMID:37951222
Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance., PMID:37795356
Exploratory analysis to predict pneumonitis during durvalumab consolidation therapy for patients with locally advanced non-small cell lung cancer from proteomic profiling of circulating extracellular vesicles., PMID:37614219
The lncRNA expression profile signature of leukemia stem cells is altered upon PI3K/mTOR inhibition: an in vitro and in silico study., PMID:37470414
TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation., PMID:37392737
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy., PMID:37337107
Effect of dextransucrase antibodies on biofilm formation and certain cariogenic activities in Streptococcus mutans., PMID:37289487
[Verification of the diagnosis of supratentorial ependymomas by real-time PCR]., PMID:37272434
Downregulation of HHLA2 inhibits ovarian cancer progression via the NF-κB signaling pathway and suppresses the expression of CA9., PMID:37210768
Living Donor Liver transplantation in an alloimmunised patient: Immunological challenges and Management in Indian Settings., PMID:37210014
Emergency ABO-incompatible living donor liver transplantation in Wilson disease-induced acute liver failure., PMID:37188013
Health-related quality of life with nivolumab plus relatlimab versus nivolumab monotherapy in patients with previously untreated unresectable or metastatic melanoma: RELATIVITY-047 trial., PMID:37167764
MC3/SAINT-O-Somes, a novel liposomal delivery system for efficient and safe delivery of siRNA into endothelial cells., PMID:36920318
Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma., PMID:36867577
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis., PMID:36711864
The longitudinal loss of islet autoantibody responses from diagnosis of type 1 diabetes occurs progressively over follow-up and is determined by low autoantibody titres, early-onset, and genetic variants., PMID:36181724
Long-term liver allograft fibrosis: A review with emphasis on idiopathic post-transplant hepatitis and chronic antibody mediated rejection., PMID:36157865
Sublytic C5b-9 Induces CCL3/4 Production and Macrophage Accumulation in Thy-1N Rats via PKC-α/p65/IRF-8 Axis., PMID:35637950
Trans-activation of eotaxin-1 by Brg1 contributes to liver regeneration., PMID:35614068
CARD9 Mediates Pancreatic Islet Beta-Cell Dysfunction Under the Duress of Hyperglycemic Stress., PMID:35362297
Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion., PMID:35314680
Identification of Growth Factors, Cytokines and Mediators Regulated by Artemisia annua L. Polyphenols (pKAL) in HCT116 Colorectal Cancer Cells: TGF-β1 and NGF-β Attenuate pKAL-Induced Anticancer Effects via NF-κB p65 Upregulation., PMID:35163520
A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains., PMID:35121656
How single-cell multi-omics builds relationships., PMID:35105969
A simple method for labeling proteins and antibodies with biotin using the proximity biotinylation enzyme TurboID., PMID:35030423
Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores., PMID:34884902
Fluvastatin enhances IL-33-mediated mast cell IL-6 and TNF production., PMID:34883342
Dynamics of epigenetic modifiers and environmentally sensitive proteins in a reptile with temperature induced sex reversal†., PMID:34849582
For research use only. Not for human or drug use.
