Catalog No.
PHF99001
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TFF2 (Ser27-His128).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Spasmolysin,SML1,TFF2,Spasmolytic polypeptide,SP,Trefoil factor 2
Purification
Purified by antigen affinity column.
Accession
Q03403
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Different Forms of TFF3 in the Human Endocervix, including a Complex with IgG Fc Binding Protein (FCGBP), and Further Aspects of the Cervico-Vaginal Innate Immune Barrier., PMID:38396964
Different Molecular Forms of TFF3 in the Human Respiratory Tract: Heterodimerization with IgG Fc Binding Protein (FCGBP) and Proteolytic Cleavage in Bronchial Secretions., PMID:36499686
Atrophic gastritis in Helicobacter pylori-infected children., PMID:35306717
The Association of Trefoil Factors with Gastric Cancer and Premalignant Lesions: A Cross-Sectional Population-Based Cohort Study., PMID:35027436
Development of Pancreatic Acinar Cell Metaplasia During Gastric Repair in a Rat Duodenal Contents Reflux Model., PMID:32440745
Subcellular Localization of the TFF Peptides xP1 and xP4 in the Xenopus laevis Gastric/Esophageal Mucosa: Different Secretion Modes Reflecting Diverse Protective Functions., PMID:31979419
Different Forms of TFF2, A Lectin of the Human Gastric Mucus Barrier: In Vitro Binding Studies., PMID:31771101
Single-cell transcriptional analyses of spasmolytic polypeptide-expressing metaplasia arising from acute drug injury and chronic inflammation in the stomach., PMID:31481545
Trefoil factor(s) and CA19.9: A promising panel for early detection of pancreatic cancer., PMID:30956167
Evidence for heightened genetic instability in precancerous spasmolytic polypeptide expressing gastric glands., PMID:30877236
Commercial Porcine Gastric Mucin Preparations, also Used as Artificial Saliva, are a Rich Source for the Lectin TFF2: In Vitro Binding Studies., PMID:30371971
Trefoil factor family 2 protein: a potential immunohistochemical marker for aiding diagnosis of lobular endocervical glandular hyperplasia and gastric-type adenocarcinoma of the uterine cervix., PMID:30324235
Effects of dietary yeast nucleotides supplementation on intestinal barrier function, intestinal microbiota, and humoral immunity in specific pathogen-free chickens., PMID:29945221
Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli., PMID:29930977
Production of Monoclonal Antibodies against Human Trefoil Factor 3 and Development of a Modified-Sandwich ELISA for Detection of Trefoil Factor 3 Homodimer in Saliva., PMID:29151819
Obstructive sleep apnea and rhonchopathy are associated with downregulation of trefoil factor family peptide 3 (TFF3)-Implications of changes in oral mucus composition., PMID:29028798
Anti-tumor efficacy evaluation of a novel monoclonal antibody targeting neutral amino acid transporter ASCT2 using patient-derived xenograft mouse models of gastric cancer., PMID:28804556
[Study on Variation of Gastroprotective Effect of Atractylodes lancea Rhizome Before and After Processing]., PMID:30132314
Effects of ezrin knockdown on the structure of gastric glandular epithelia., PMID:26329936
Heterogeneous Nuclear Ribonucleoprotein A1 Improves the Intestinal Injury by Regulating Apoptosis Through Trefoil Factor 2 in Mice with Anti-CD3-induced Enteritis., PMID:25901972
[Effect of Rhizoma Atractylodis extract in protecting gastric mucosa and modulating gastrointestinal immune function in a rat model of spleen deficiency]., PMID:25818777
Trefoil factor family peptides TFF1 and TFF3 in the nervous tissues of developing mouse embryo., PMID:25725142
Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid., PMID:25481080
Establishment of a three-dimensional culture system of gastric stem cells supporting mucous cell differentiation using microfibrous polycaprolactone scaffolds., PMID:25345659
Stromal cell derived factor-2 (Sdf2): a novel protein expressed in mouse., PMID:24878610
Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China., PMID:24720760
A study of gene expression markers for predictive significance for bevacizumab benefit in patients with metastatic colon cancer: a translational research study of the Hellenic Cooperative Oncology Group (HeCOG)., PMID:24555920
A variant form of the human deleted in malignant brain tumor 1 (DMBT1) gene shows increased expression in inflammatory bowel diseases and interacts with dimeric trefoil factor 3 (TFF3)., PMID:23691218
Influence of Helicobacter pylori status and eradication on the serum levels of trefoil factors and pepsinogen test: serum trefoil factor 3 is a stable biomarker., PMID:22907485
Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation., PMID:22212092
Pathophysiological investigation of the gastric surface mucous gel layer of patients with Helicobacter pylori infection by using immunoassays for trefoil factor family 2 and gastric gland mucous cell-type mucin in gastric juice., PMID:21559742
The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk., PMID:21455714
Nitric oxide induces HIF-1α stabilization and expression of intestinal trefoil factor in the damaged rat jejunum and modulates ulcer healing., PMID:21305324
Trefoil factor family peptides in human saliva and cyclical cervical mucus. Method evaluation and results on healthy individuals., PMID:21275809
A chimeric peptide of intestinal trefoil factor containing cholesteryl ester transfer protein B cell epitope significantly inhibits atherosclerosis in rabbits after oral administration., PMID:21192999
An immunohistochemical profile of the so-called bile duct adenoma: clues to pathogenesis., PMID:20679879
Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia., PMID:20625512
Synthesis and localization of trefoil factor family (TFF) peptides in the human urinary tract and TFF2 excretion into the urine., PMID:20063012
Altered gastric chief cell lineage differentiation in histamine-deficient mice., PMID:19359424
Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines., PMID:19064997
Betagamma-CAT, a non-lens betagamma-crystallin and trefoil factor complex from amphibian skin secretions, caused endothelium-dependent myocardial depression in isolated rabbit hearts., PMID:18602941
A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications., PMID:18335045
Characterization of the activation domain of the Rad53 checkpoint kinase., PMID:18287812
Emergence of spasmolytic polypeptide-expressing metaplasia in Mongolian gerbils infected with Helicobacter pylori., PMID:18004396
Tissue localization of human trefoil factors 1, 2, and 3., PMID:17242463
Localization of TFF3 peptide in human esophageal submucosal glands and gastric cardia: differentiation of two types of gastric pit cells along the rostro-caudal axis., PMID:17216196
Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses., PMID:17101660
Induced trefoil factor family 1 expression by trans-differentiating Clara cells in a murine asthma model., PMID:16990615
Identification of blottin: a novel gastric trefoil factor family-2 binding protein., PMID:16888721
Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium., PMID:16410243
For research use only. Not for human or drug use.
