Catalog No.
PHF90901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TAGLN (Met1-Ser201).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
SM22-alpha,WS3-10,Smooth muscle protein 22-alpha,SM22,Transgelin,TAGLN,Protein WS3-10,22 kDa actin-binding protein
Purification
Purified by antigen affinity column.
Accession
Q01995
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series., PMID:39836188
Cancer-Associated Fibroblast Proteins as Potential Targets against Colorectal Cancers., PMID:39335130
TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve disease., PMID:37908840
Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning., PMID:36211422
Desmoplastic Small Round Cell Tumor of the Uterus: A Report of Molecularly Confirmed Case with EWSR1-WT1 Fusion., PMID:35626339
TAGLN mediated stiffness-regulated ovarian cancer progression via RhoA/ROCK pathway., PMID:34538264
Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype., PMID:33420328
Recombinant transgelin-like protein 1 from Mytilus shell induces formation of CaCO3 polymorphic crystals in vitro., PMID:32902197
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells., PMID:32813135
Comparison of the efficiency of transgelin, smooth muscle myosin, and CD31 antibodies for the assessment of vascular tumor invasion and free tumor deposits in gastric, pancreatic, and colorectal adenocarcinomas., PMID:32031118
[OxLDL/β2GPI/anti-β2GPI complex promotes calcification and inflammatory cytokine expression in A7r5 cells]., PMID:31894004
Vanadium Derivative Exposure Promotes Functional Alterations of VSMCs and Consequent Atherosclerosis via ROS/p38/NF-κB-Mediated IL-6 Production., PMID:31817202
Evaluation of canine 2D cell cultures as models of myxomatous mitral valve degeneration., PMID:31415646
Antibodies against specific extractable nuclear antigens (ENAs) as diagnostic and prognostic tools and inducers of a profibrotic phenotype in cultured human skin fibroblasts: are they functional?, PMID:31234888
Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain., PMID:30485540
Mechanoregulation of SM22α/Transgelin., PMID:28898058
Transgelin mediates transforming growth factor-β1-induced proliferation of human periodontal ligament cells., PMID:28590058
Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells., PMID:28510269
The sheep (Ovis aries) muscle proteome: Decoding the mechanisms of tolerance to Seasonal Weight Loss using label-free proteomics., PMID:28366878
Functional significance of transgelin-2 in uterine cervical squamous cell carcinoma., PMID:26891454
Regulation of the Na(+)-K(+)-2Cl(-) cotransporter by cGMP/cGMP-dependent protein kinase I after furosemide administration., PMID:26183401
Immunohistochemical panel to differentiate endometrial stromal sarcoma, uterine leiomyosarcoma and leiomyoma: something old and something new., PMID:25991737
Genetic Evidence Supports a Major Role for Akt1 in VSMCs During Atherogenesis., PMID:25868464
The glomerular parietal epithelial cell's responses are influenced by SM22 alpha levels., PMID:25376243
Loss of PiT-1 results in abnormal endocytosis in the yolk sac visceral endoderm., PMID:25138534
Proinflammatory role of stem cells in abdominal aortic aneurysms., PMID:24997808
Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling., PMID:24816588
Transgelin: an androgen-dependent protein identified in the seminal vesicles of three Saharan rodents., PMID:23906482
Disruption of canonical TGFβ-signaling in murine coronary progenitor cells by low level arsenic., PMID:23732083
Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine., PMID:23413114
Cross-reacting antibacterial auto-antibodies are produced within coronary atherosclerotic plaques of acute coronary syndrome patients., PMID:22879930
Transgelin is a marker of repopulating mesangial cells after injury and promotes their proliferation and migration., PMID:22469697
CD99 is a novel prognostic stromal marker in non-small cell lung cancer., PMID:22392539
Quantitative histological analysis of SM22α (transgelin) in an adriamycin-induced focal segmental glomerulosclerosis model., PMID:22205114
Using proteomic approach to identify tumor-associated proteins as biomarkers in human esophageal squamous cell carcinoma., PMID:21517111
Role of smooth muscle protein SM22α in glomerular epithelial cell injury., PMID:21289056
Injured kidney cells express SM22α (transgelin): Unique features distinct from α-smooth muscle actin (αSMA)., PMID:21272134
Molecular cloning and characterization of transgelin-like proteins mainly transcribed in newborn larvae of Trichinella spp., PMID:21242032
Gene expression analysis of HUVEC in response to TF-binding., PMID:21186047
The cell surface structure of tumor endothelial marker 8 (TEM8) is regulated by the actin cytoskeleton., PMID:21129411
miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness., PMID:20818426
All-trans retinoic acid promotes smooth muscle cell differentiation of rabbit bone marrow-derived mesenchymal stem cells., PMID:20593513
Characterization of smooth muscle differentiation of purified human skeletal muscle-derived cells., PMID:20132408
Transgelin induces apoptosis of human prostate LNCaP cells through its interaction with p53., PMID:20098441
Human embryonic stem cell-derived vascular progenitor cells capable of endothelial and smooth muscle cell function., PMID:20067819
Association of the actin-binding protein transgelin with lymph node metastasis in human colorectal cancer., PMID:19724680
Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element., PMID:19344627
Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release., PMID:19171648
Label-free detection of cancer biomarker candidates using surface plasmon resonance imaging., PMID:18958451
Arterial calcification: a tumor necrosis factor-alpha mediated vascular Wnt-opathy., PMID:18433704