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Anti-NKCC1 Antibody (N161/1)

Catalog #:   RHF07601 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHF07601

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

SLC12A2, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2, Solute carrier family 12 member 2, NKCC1, Basolateral Na-K-Cl symporter

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N161/1

Data Image
References

A Cftr-independent, Ano1-rich seawater-adaptive ionocyte in sea lamprey gills., PMID:40007443

Maternal immune activation alters the GABAergic system in the prefrontal cortex of female rat offspring: Role of interleukin-6., PMID:39884421

Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development., PMID:36573432

Targeting the Cation-Chloride Co-Transporter NKCC1 to Re-Establish GABAergic Inhibition and an Appropriate Excitatory/Inhibitory Balance in Selective Neuronal Circuits: A Novel Approach for the Treatment of Alzheimer's Disease., PMID:35741668

The combination of hair follicle-specific marker LHX2 and co-expressed marker can distinguish between sweat gland placodes and hair placodes in rat., PMID:34581932

NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data., PMID:33291778

Staurosporine and NEM mainly impair WNK-SPAK/OSR1 mediated phosphorylation of KCC2 and NKCC1., PMID:32413057

Salinity-dependent expression of ncc2 in opercular epithelium and gill of mummichog (Fundulus heteroclitus)., PMID:31980891

Novel Treatment Targets Based on Insights in the Etiology of Depression: Role of IL-6 Trans-Signaling and Stress-Induced Elevation of Glutamate and ATP., PMID:31362361

Differential antigen expression between human eccrine sweat glands and hair follicles/pilosebaceous units., PMID:31062203

Alteration in branchial NKA and NKCC ion-transporter expression and ionocyte distribution in adult hilsa during up-river migration., PMID:30483930

Epithelial disruptions, but not immune cell invasion, induced secretory dysfunction following innate immune activation in a novel model of acute salivary gland injury., PMID:29160910

The modulation of the phosphorylation status of NKCC1 in organ cultured bovine lenses: Implications for the regulation of fiber cell and overall lens volume., PMID:28818393

Depolarizing γ-aminobutyric acid contributes to glutamatergic network rewiring in epilepsy., PMID:28074534

Effect of vasopressin on Na(+)-K(+)-2Cl(-) cotransporter (NKCC) and the signaling mechanisms on the murine late distal colon., PMID:26656758

A sea urchin Na(+)K(+)2Cl(-) cotransporter is involved in the maintenance of calcification-relevant cytoplasmic cords in Strongylocentrotus droebachiensis larvae., PMID:25986441

Combustion smoke-induced inflammation in the olfactory bulb of adult rats., PMID:25297558

Age-related change in the expression of NKCC1 in the cochlear lateral wall of C57BL/6J mice., PMID:25220727

Targeted expression of anoctamin calcium-activated chloride channels in rod photoreceptor terminals of the rodent retina., PMID:23557741

High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells., PMID:23506056

Lubiprostone targets prostanoid signaling and promotes ion transporter trafficking, mucus exocytosis, and contractility., PMID:22923315

Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation., PMID:22570591

Molecular and functional expression of cation-chloride cotransporters in dorsal root ganglion neurons during postnatal maturation., PMID:22457464

Cellular distribution of NKCC2 in the gastric mucosa and its response to short-term osmotic shock., PMID:22388656

Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1., PMID:22223659

Changes of chloride channels in the lacrimal glands of a rabbit model of Sjögren syndrome., PMID:22157573

A prolonged experimental febrile seizure results in motor map reorganization in adulthood., PMID:22044736

An autocrine neuronal interleukin-6 loop mediates chloride accumulation and NKCC1 phosphorylation in axotomized sensory neurons., PMID:21940443

Role of NKCC in BK channel-mediated net K⁺ secretion in the CCD., PMID:21816753

Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells., PMID:21464992

Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma., PMID:20461409

Expression of the sodium potassium chloride cotransporter (NKCC1) and sodium chloride cotransporter (NCC) and their effects on rat lens transparency., PMID:20458365

Phosphorylation state of the Na+-K+-Cl- cotransporter (NKCC1) in the gills of Atlantic killifish (Fundulus heteroclitus) during acclimation to water of varying salinity., PMID:20400641

Duct system of the rabbit lacrimal gland: structural characteristics and role in lacrimal secretion., PMID:20107177

Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominant-negative effect of the AF splice variant., PMID:19854835

Chloride Is essential for capacitation and for the capacitation-associated increase in tyrosine phosphorylation., PMID:18957426

Expression of aquaporin1, 3, and 4, NKCC1, and NKCC2 in the human endolymphatic sac., PMID:18606512

Glycine input induces the synaptic facilitation in salamander rod photoreceptors., PMID:18553216

Focal adhesion kinase and beta1 integrin regulation of Na+, K+, 2Cl- cotransporter in osmosensing ion transporting cells of killifish, Fundulus heteroclitus., PMID:18455940

Spatial and temporal distribution patterns of Na-K-2Cl cotransporter in adult and developing mouse retinas., PMID:18442435

Roles of basolateral solute uptake via NKCC1 and of myosin II in vasopressin-induced cell swelling in inner medullary collecting duct., PMID:18417545

NKCC1 phosphorylation stimulates neurite growth of injured adult sensory neurons., PMID:17581962

SLC26A7 can function as a chloride-loading mechanism in parietal cells., PMID:17404755

Interleukin-1beta upregulates Na+-K+-2Cl- cotransporter in human middle ear epithelia., PMID:17211836

Protein expression and mRNA cellular distribution of the NKCC1 cotransporter in the dorsal root and trigeminal ganglia of the rat., PMID:16904086

Gene expression in rat lacrimal gland duct cells collected using laser capture microdissection: evidence for K+ secretion by duct cells., PMID:16638994

The fine-structural distribution of G-protein receptor kinase 3, beta-arrestin-2, Ca2+/calmodulin-dependent protein kinase II and phosphodiesterase PDE1C2, and a Cl(-)-cotransporter in rodent olfactory epithelia., PMID:16374707

Successful treatment of a patient with primary Sjögren's syndrome with Rituximab., PMID:16283417

Regulation of erythrocyte Na-K-2Cl cotransport by threonine phosphorylation., PMID:15996636

Predominant constitutive CFTR conductance in small airways., PMID:15655076

Datasheet

Document Download

Anti-NKCC1 Antibody (N161/1).pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-NKCC1 Antibody (N161/1) [RHF07601]
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