Catalog No.
RHE38803
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
EAAC1, EAAT3, Sodium-dependent glutamate/aspartate transporter 3, Solute carrier family 1 member 1, Excitatory amino-acid carrier 1, SLC1A1, Excitatory amino acid transporter 3, Neuronal and epithelial glutamate transporter
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N420/64
Systemic L-Buthionine -S-R-Sulfoximine Treatment Increases Plasma NGF and Upregulates L-cys/L-cys2 Transporter and γ-Glutamylcysteine Ligase mRNAs Through the NGF/TrkA/Akt/Nrf2 Pathway in the Striatum., PMID:31396052
Reduced responses to glutamate receptor agonists follow loss of astrocytes and astroglial glutamate markers in the nucleus tractus solitarii., PMID:28270593
Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1., PMID:26739563
Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington's disease mice., PMID:25526803
The rates of postmortem proteolysis of glutamate transporters differ dramatically between cells and between transporter subtypes., PMID:22859703
The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS., PMID:22539860
Changes in glutamate transporter expression in mouse forebrain areas following focal ischemia., PMID:21911209
Expression, distribution and glutamate uptake activity of high affinity-excitatory aminoacid transporters in in vitro cultures of embryonic rat dorsal root ganglia., PMID:21726604
Platelet-derived growth factor receptor alpha is associated with oxidative stress-induced retinal cell death., PMID:21405954
Group I mGluR-regulated translation of the neuronal glutamate transporter, excitatory amino acid carrier 1., PMID:21371038
Glutamate clearance mechanisms in resected cortical dysplasia., PMID:21073256
An indirect basal ganglia pathway in anuran amphibians?, PMID:20206683
Expression and distribution of 'high affinity' glutamate transporters GLT1, GLAST, EAAC1 and of GCPII in the rat peripheral nervous system., PMID:19014361
Downregulation of glial glutamate transporters after dopamine denervation in the striatum of 6-hydroxydopamine-lesioned rats., PMID:18831527
Amitriptyline induces nuclear transcription factor-kappaB-dependent glutamate transporter upregulation in chronic morphine-infused rats., PMID:18400403
Glutamate receptor expression in multiple sclerosis lesions., PMID:17924980
Neural localization of addicsin in mouse brain., PMID:17897781
Regional distribution of sodium-dependent excitatory amino acid transporters in rat spinal cord., PMID:17684893
Alterations of amino acids and glutamate transport in the DBA/2J mouse retina; possible clues to degeneration., PMID:17226020
Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini., PMID:15569258
Expression of glutamate transporters in rat cardiomyocytes and their localization in the T-tubular system., PMID:15385585
Increased luminal pH in the epididymis of infertile c-ros knockout mice and the expression of sodium-hydrogen exchangers and vacuolar proton pump H+-ATPase., PMID:15095336
Identification of glutamate receptors and transporters in mouse and human sperm., PMID:14662797
Neuronal glutamate transporter EAAT4 is expressed in astrocytes., PMID:12951653
Expression of glutamate transporters in human and rat retina and rat optic nerve., PMID:12898275
Decreased expression of glutamate transporters in genetic absence epilepsy rats before seizure occurrence., PMID:11953453
Increased expression of the neuronal glutamate transporter (EAAT3/EAAC1) in hippocampal and neocortical epilepsy., PMID:11906504
Evaluation of 3-nitrotyrosine as a marker for 3-nitropropionic acid-induced oxidative stress in Lewis and Wistar rats and strain-specific whole brain spheroid cultures., PMID:11897084
Nigrostriatal denervation does not affect glutamate transporter mRNA expression but subsequent levodopa treatment selectively increases GLT1 mRNA and protein expression in the rat striatum., PMID:11723182
Glutamate transporter EAAC1 in the cat periaqueductal gray matter., PMID:11698134
Glutamate transporter EAAC1 is expressed on Müller cells of lower vertebrate retinas., PMID:11599005
Characteristics of L-aspartate transport and expression of EAAC-1 in sarcolemmal vesicles and isolated cells from rat heart., PMID:11557236
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1., PMID:11426296
Calcium channels coupled to depolarization-evoked glutamate release in the myenteric plexus of guinea-pig ileum., PMID:11068152
Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity., PMID:11031254
The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms., PMID:10812201
Glutamate transporter EAAC1 is expressed in neurons and glial cells in the rat nervous system., PMID:10417812
Expression of glutamate transporters in rat optic nerve oligodendrocytes., PMID:10383611
Expression of glutamate transporters in the adult bovine corpus callosum., PMID:10216228
The glutamate transporter, GLT-1, is expressed in cultured hippocampal neurons., PMID:9761452
Comparative analysis of glutamate transporter expression in rat brain using differential double in situ hybridization., PMID:9683064
Reduction of GABA and glutamate transporter messenger RNAs in the severe-seizure genetically epilepsy-prone rat., PMID:9681960
Identification of somatostatin sst2(a) receptor expressing neurones in central regions involved in nociception., PMID:9666064
Neuronal expression of the glutamate transporter GLT-1 in hippocampal microcultures., PMID:9614226
EAAC1, a high-affinity glutamate tranporter, is localized to astrocytes and gabaergic neurons besides pyramidal cells in the rat cerebral cortex., PMID:9542890
Rat hepatoma cells express novel transport systems for glutamine and glutamate in addition to those present in normal rat hepatocytes., PMID:9461518
Localization of the high-affinity glutamate transporter EAAC1 in rat kidney., PMID:9435692
Immunohistochemical localization of the neuron-specific glutamate transporter EAAC1 (EAAT3) in rat brain and spinal cord revealed by a novel monoclonal antibody., PMID:9409715
Functional expression of a GLT-1 type Na+-dependent glutamate transporter in rat pinealocytes., PMID:9326278
Glutamate transporter protein subtypes are expressed differentially during rat CNS development., PMID:9334410
For research use only. Not for human or drug use.
