Catalog No.
PHF78901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VLDLR (Lys418-Ala722).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Very low-density lipoprotein receptor,VLDL receptor,VLDL-R,VLDLR
Purification
Purified by antigen affinity column.
Accession
P98155
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Proteomic Analysis of Human Chylomicron Remnants Isolated by Apolipoprotein B-48 Immunoprecipitation., PMID:39085140
Understanding the role of membrane cholesterol upon Epstein Barr virus infection in astroglial cells., PMID:37876925
Quantification of soluble very low-density lipoprotein receptor in human serum using a sandwich enzyme-linked immunosorbent assay., PMID:37781344
The impact of the PCSK-9/VLDL-Receptor axis on inflammatory cell polarization., PMID:36356495
Expanding Biology of PCSK9: Roles in Atherosclerosis and Beyond., PMID:35904732
Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration., PMID:34820908
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity., PMID:34731223
Intracellular Accumulation of IFN-λ4 Induces ER Stress and Results in Anti-Cirrhotic but Pro-HCV Effects., PMID:34497603
PCSK9 and cancer: Rethinking the link., PMID:34058443
Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway., PMID:30127721
Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease., PMID:29289645
PCSK9 signaling pathways and their potential importance in clinical practice., PMID:29209441
Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9., PMID:28750079
The Proprotein Convertases in Hypercholesterolemia and Cardiovascular Diseases: Emphasis on Proprotein Convertase Subtilisin/Kexin 9., PMID:27920219
Anti-VLDL receptor monoclonal antibodies inhibit fibrin-VLDL receptor interaction and reduce fibrin-dependent leukocyte transmigration., PMID:27580629
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus., PMID:27152966
New developments in proprotein convertase subtilisin-kexin 9's biology and clinical implications., PMID:27031271
Targeting PCSK9 for therapeutic gains: Have we addressed all the concerns?, PMID:26987067
Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex., PMID:25308109
Receptor heterodimerization as a novel mechanism for the regulation of Wnt/β-catenin signaling., PMID:25271056
The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses., PMID:24733846
Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts., PMID:23142657
miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis., PMID:22115756
Identification of VLDLR as a novel endothelial cell receptor for fibrin that modulates fibrin-dependent transendothelial migration of leukocytes., PMID:22096238
The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction., PMID:21670500
Apolipoprotein E induces antiinflammatory phenotype in macrophages., PMID:21350196
Resveratrol inhibits pathologic retinal neovascularization in Vldlr(-/-) mice., PMID:21282584
Ceruloplasmin-induced aggregation of P19 neurons involves a serine protease activity and is accompanied by reelin cleavage., PMID:20188154
Overproduced interleukin 6 decreases blood lipid levels via upregulation of very-low-density lipoprotein receptor., PMID:19433409
Loss of VLDL receptor activates retinal vascular endothelial cells and promotes angiogenesis., PMID:18936153
The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII., PMID:18277139
Expression of VLDLR in the retina and evolution of subretinal neovascularization in the knockout mouse model's retinal angiomatous proliferation., PMID:18172119
Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells., PMID:18032585
Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization., PMID:17890782
Reelin, very-low-density lipoprotein receptor, and apolipoprotein E receptor 2 control somatic NMDA receptor composition during hippocampal maturation in vitro., PMID:15987942
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia., PMID:15269711
Twelve receptor molecules attach per viral particle of human rhinovirus serotype 2 via multiple modules., PMID:15196928
Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway., PMID:14715136
The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor., PMID:12169628
Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling., PMID:12077184
Significance of the variant and full-length forms of the very low density lipoprotein receptor in brain., PMID:11743951
Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotes MCF-7 cell growth., PMID:11266465
[Corticohistogenesis and Reelin signal cascade]., PMID:11215402
Reelin binds alpha3beta1 integrin and inhibits neuronal migration., PMID:10939329
Very low-density lipoprotein receptor in fetal intestine and gastric adenocarcinoma cells., PMID:10629142
Reelin is a ligand for lipoprotein receptors., PMID:10571240
The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro., PMID:10066806
Very-low-density lipoprotein receptor fragment shed from HeLa cells inhibits human rhinovirus infection., PMID:9811769
A variant very low density lipoprotein receptor lacking 84 base pairs of O-linked sugar domain in the human brain myelin., PMID:9630508
Expression of the VLDL receptor in endothelial cells., PMID:8630667