Anti-Dopamine D2 receptor Antibody (N186/26)

Catalog No.

RHD04803

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

D(2) dopamine receptor, Dopamine D2 receptor, DRD2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N186/26

Suppression of mechanical hypersensitivity and change in the expression of the dopamine D2 receptor by administration of anti-CGRP antibody into the trigeminal ganglion in trigeminal neuropathic pain model rats., PMID:40367052

Valproic acid promotes transcriptional activation of Drd2 by mediating histone acetylation to inhibit the mTOR-Pttg1 signaling axis and exerts anti-PitNETs activity., PMID:40220407

Anti-dopamine receptor 2 antibody encephalitis in adults: a case report., PMID:39425067

Dopamine receptor autoantibody signaling in infectious sequelae differentiates movement versus neuropsychiatric disorders., PMID:39325550

DRD4 promotes chemo-resistance and cancer stem cell-like phenotypes by mediating the activation of the Akt/β-catenin signaling axis in liver cancer., PMID:39174739

The Black Book of Psychotropic Dosing and Monitoring., PMID:38993656

Case report: Successful treatment of an anti-D2R and DPPX antibody-associated autoimmune encephalitis patient with high-dose methylprednisolone and intravenous immunoglobulin., PMID:38469308

Neurological autoantibody prevalence in chronic epilepsy: Clinical and neuropathologic findings., PMID:38183825

Efficacy of Antidopaminergic Pharmacotherapy in Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS): A Case Report., PMID:37753029

Antiangiogenic Effect of Dopamine and Dopaminergic Agonists as an Adjuvant Therapeutic Option in the Treatment of Cancer, Endometriosis, and Osteoarthritis., PMID:37373348

Hypothesizing That Pediatric Autoimmune Neuropsychiatric Associated Streptococcal (PANDAS) Causes Rapid Onset of Reward Deficiency Syndrome (RDS) Behaviors and May Require Induction of "Dopamine Homeostasis"., PMID:36407790

Effects of Cyclosporine A and Adalimumab on the expression profiles histaminergic system-associated genes and microRNAs regulating these genes in HaCaT cells., PMID:35899934

Dopamine D2 and Serotonin 5-HT1A Dimeric Receptor-Binding Monomeric Antibody scFv as a Potential Ligand for Carrying Drugs Targeting Selected Areas of the Brain., PMID:35740874

Cerebroventricular administration of anti-calcitonin gene-related peptide antibody reduces the increase of dopamine D2 receptor observed in the trigeminal spinal subnucleus caudalis following infraorbital nerve ligation., PMID:35569379

Continuous but not intermittent theta burst stimulation decreases striatal dopamine release and cortical excitability., PMID:35526596

The Inhibitory Effect of Selected D2 Dopaminergic Receptor Agonists on VEGF-Dependent Neovascularization in Zebrafish Larvae: Potential New Therapy in Ophthalmic Diseases., PMID:35406766

Synaptotagmins 1 and 7 Play Complementary Roles in Somatodendritic Dopamine Release., PMID:35361702

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine., PMID:35325034

Seronegative Autoimmune Basal Ganglia Encephalitis Presenting as Acute Parkinsonism and Refractory Faciobrachial Seizures: A Case Report., PMID:35186605

HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk., PMID:35062349

Subcellular localization of D2 receptors in the murine substantia nigra., PMID:34854963

Neuroprotective effects of dopamine D2 receptor agonist on neuroinflammatory injury in olfactory bulb neurons in vitro and in vivo in a mouse model of allergic rhinitis., PMID:34624383

Alum and metoclopramide synergistically enhance cellular and humoral immunity after immunization with heat-killed Salmonella typhimurium vaccine., PMID:34607234

[Blockade of D1-like dopaminergic receptors suppresses Th17-cell function in multiple sclerosis]., PMID:34387452

Dopamine Receptor-Mediated Binding and Cellular Uptake of Polydopamine-Coated Nanoparticles., PMID:34379407

Repeated cocaine administration upregulates CB2 receptor expression in striatal medium-spiny neurons that express dopamine D1 receptors in mice., PMID:34316031

Tumor suppressor DRD2 facilitates M1 macrophages and restricts NF-κB signaling to trigger pyroptosis in breast cancer., PMID:33859743

New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling., PMID:33859231

Activity-dependent somatodendritic dopamine release in the substantia nigra autoinhibits the releasing neuron., PMID:33826884

Development of a New Polymeric Nanocarrier Dedicated to Controlled Clozapine Delivery at the Dopamine D2-Serotonin 5-HT1A Heteromers., PMID:33805130

Cytokeratin 8/18-negative somatotroph pituitary neuroendocrine tumours (PitNETs, adenomas) show variable morphological features and do not represent a clinicopathologically distinct entity., PMID:33738859

Neurochemical regulation of Aedes aegypti salivary gland function., PMID:33460707

Levosulpiride Increases the Levels of Prolactin and Antiangiogenic Vasoinhibin in the Vitreous of Patients with Proliferative Diabetic Retinopathy., PMID:32879783

Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections., PMID:32670106

Can anti-dopamine D2 receptor autoantibodies explain fluctuations of tic severity?, PMID:32662071

Anti-dopamine D2 receptor antibodies in chronic tic disorders., PMID:32644201

Pimavanserin exhibits serotonin 5-HT2A receptor inverse agonism for Gαi1- and neutral antagonism for Gαq/11-proteins in human brain cortex., PMID:32517960

Perphenazine Attenuates the Pro-Inflammatory Responses in Mouse Models of Th2-Type Allergic Dermatitis., PMID:32375285

Dystonia: Sparse Synapses for D2 Receptors in Striatum of a DYT1 Knock-out Mouse Model., PMID:32041188

Detection of G Protein-Coupled Receptor Complexes in Postmortem Human Brain by Proximity Ligation Assay., PMID:31943888

Neuroimmunological antibody-mediated encephalitis and implications for diagnosis and therapy in neuropsychiatry., PMID:31791436

PET Imaging of Pancreatic Dopamine D2 and D3 Receptor Density with 11C-(+)-PHNO in Type 1 Diabetes., PMID:31601695

Akinetic mutism and status epilepticus due to Epstein Barr virus encephalitis., PMID:31470359

Bovine dopamine type-2 receptor SNP has no effect on growth, semen characteristics and prolactin concentrations in beef bulls treated with a dopamine agonist., PMID:31208851

Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration., PMID:30927362

Neuroreceptor kinetics in rats repeatedly exposed to quinpirole as a model for OCD., PMID:30845202

Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation., PMID:30003938

Child Neurology: Treatable bilateral striatal lesions related to anti-dopamine 2 receptor autoimmunity., PMID:29987177

[Pituitary lactotroph adenomas resistant to dopamine agonist treatment: histological and immunohistochemical characteristics]., PMID:29927438

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion., PMID:29806846

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