Catalog No.
RHC98701
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
PG-M, Glial hyaluronate-binding protein, CSPG2, Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Large fibroblast proteoglycan, GHAP, Chondroitin sulfate proteoglycan 2, VCAN
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N351/23
Localization, Proteolytic Processing, and Binding Partners of Versican Isoforms in Vascular Lesions of Pulmonary Arterial Hypertension., PMID:40219589
Enhancing the Purity and Intrinsic Properties of Ovine Dermal Papilla Cells through Flow Cytometry Sorting and Cellular Interactions., PMID:40211848
Soluble Proteoglycans and Proteoglycan Fragments as Biomarkers of Pathological Extracellular Matrix Remodeling., PMID:39600538
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development., PMID:38750698
Focal clusters of peri-synaptic matrix contribute to activity-dependent plasticity and memory in mice., PMID:38676925
Developmental patterns of extracellular matrix molecules in the embryonic and postnatal mouse hindbrain., PMID:38496826
Determination of Versikine Levels by Enzyme-Linked Immunosorbent Assay (ELISA)., PMID:38038934
TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells., PMID:37461061
V3: an enigmatic isoform of the proteoglycan versican., PMID:37399500
Knockdown of versican 1 in lung fibroblasts aggravates Lipopolysaccharide-induced acute inflammation through up-regulation of the SP1-Toll-like Receptor 2-NF-κB Axis: a potential barrier to promising Versican-targeted therapy., PMID:37311354
An immunohistochemical study of matrix components in primary and secondary cartilages of embryonic chick skull., PMID:37277025
An Assessment and Comparison of the Efficacy of Two Licensed Tetravalent Leptospira Vaccines for Dogs Using an Improved Challenge Model., PMID:36146551
Expression of VCAN and its receptors in canine mammary carcinomas with or without myoepithelial proliferation., PMID:34399281
A new mouse mutant with cleavage-resistant versican and isoform-specific versican mutants demonstrate that proteolysis at the Glu441-Ala442 peptide bond in the V1 isoform is essential for interdigital web regression., PMID:34195596
An anti-ADAMTS1 treatment relieved muscle dysfunction and fibrosis in dystrophic mice., PMID:34175316
Extracellular Matrix Deposition and Remodeling after Corneal Alkali Burn in Mice., PMID:34071909
Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles., PMID:32156081
Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification., PMID:31959784
Targeting of stromal versican by miR-144/199 inhibits multiple myeloma by downregulating FAK/STAT3 signalling., PMID:31532704
Evaluation of canine 2D cell cultures as models of myxomatous mitral valve degeneration., PMID:31415646
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells., PMID:30716431
A Retrospective Analysis of the Cartilage Kunitz Protease Inhibitory Proteins Identifies These as Members of the Inter-α-Trypsin Inhibitor Superfamily with Potential Roles in the Protection of the Articulatory Surface., PMID:30678366
Anti-β2 -glycoprotein I antibody with DNA binding activity enters living monocytes via cell surface DNA and induces tissue factor expression., PMID:30368780
A Serological Biomarker of Versican Degradation is Associated with Mortality Following Acute Exacerbations of Idiopathic Interstitial Pneumonia., PMID:29728109
Analysis of proteoglycan expression in human dental pulp., PMID:29567548
Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection., PMID:29515038
High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats., PMID:28594849
Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer., PMID:28320945
Cell Therapy of Corneal Diseases., PMID:27631350
Influence of Radiation Exposure During Radiotherapy. Evidence for the Increase of Versican and Heparin-Binding EGF-like Growth Factor Concentrations., PMID:27386634
Gonadotropin and tumorigenesis: Direct and indirect effects on inflammatory and immunosuppressive mediators and invasion., PMID:27152491
Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium., PMID:27143554
Kinetics of versican-expressing macrophages in bone marrow after cord blood stem cell transplantation for treatment of acute myelogenous leukaemia., PMID:26951084
[Effect of antibacterial peptide hCAP18/LL-37 on ovarian cancer microenvironment and the regulatory mechanism of its expression]., PMID:26813589
Sonic hedgehog controls enteric nervous system development by patterning the extracellular matrix., PMID:26674309
Review: Enthesitis: New Insights Into Pathogenesis, Diagnostic Modalities, and Treatment., PMID:26473401
Versican localizes to the nucleus in proliferating mesenchymal cells., PMID:26395512
Natural progression of atherosclerosis from pathologic intimal thickening to late fibroatheroma in human coronary arteries: A pathology study., PMID:26058741
Inhibition of hyaluronan synthesis alters sulfated glycosaminoglycans deposition during chondrogenic differentiation in ATDC5 cells., PMID:25929745
Neuronally produced versican V2 renders C-fiber nociceptors IB4 -positive., PMID:25845936
Molecular composition and expression pattern of the extracellular matrix in a mossy fiber-generating precerebellar nucleus of rat, the prepositus hypoglossi., PMID:25817362
Diabetes mellitus affects activity of calcium/calmodulin-dependent protein kinase II alpha in rat trigeminal ganglia., PMID:25701274
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling., PMID:25452390
Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth., PMID:25445787
Isolation and purification of versican and analysis of versican proteolysis., PMID:25325983
Determinants of versican-V1 proteoglycan processing by the metalloproteinase ADAMTS5., PMID:25122765
The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis., PMID:24444773
The molecular composition of the extracellular matrix of the human iliolumbar ligament., PMID:24139866
Glycosyltransferases and glycosaminoglycans in bleomycin and transforming growth factor-β1-induced pulmonary fibrosis., PMID:24127863
Fibrotic remodeling of tissue-engineered skin with deep dermal fibroblasts is reduced by keratinocytes., PMID:24090416
For research use only. Not for human or drug use.
