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Anti-Ataxin-1 Antibody (N76/8)

Catalog #:   RHC51603 Specific References (40) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHC51603

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

BOAT, Brother of ataxin-1, ATXN1L, BOAT1, Ataxin-1-like, Brother of ATXN1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N76/8

Data Image
References

Accurate Quantification of Mutant and Wild-Type polyQ Proteins Using Simple Western Capillary Immunoassays., PMID:40450087

Construction and validation of a synthetic phage-displayed nanobody library., PMID:39198226

TR-FRET-Based Immunoassay to Measure Ataxin-2 as a Target Engagement Marker in Spinocerebellar Ataxia Type 2., PMID:36894829

Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1., PMID:35906672

The novel multiple sclerosis susceptibility gene ATXN1 regulates B cell receptor signaling in B-1a cells., PMID:33478569

A new structure from cardiac cells cultured in vitro: Cardiomyocyte-annulation of neonatal rats., PMID:31245874

CD4+ TSCMs in the Bone Marrow Assist in Maturation of Antibodies against Influenza in Mice., PMID:30733641

Differentiation of Club Cells to Alveolar Epithelial Cells In Vitro., PMID:28128362

Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells., PMID:27428326

A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1., PMID:25988806

Presenile onset of spinocerebellar ataxia type 1 presenting with conspicuous psychiatric symptoms and widespread anti-expanded polyglutamine antibody- and fused in sarcoma antibody-immunopositive pathology., PMID:25920043

Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition., PMID:24706768

An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein., PMID:23760502

Reprint of: Expression and purification of ataxin-1 protein., PMID:21893199

Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy., PMID:21384195

SUMO-1 interacts with mutant ataxin-1 and colocalizes to its aggregates in Purkinje cells of SCA1 transgenic mice., PMID:21308649

Expression and purification of ataxin-1 protein., PMID:20304006

BMP-2 and FGF-2 synergistically facilitate adoption of a cardiac phenotype in somatic bone marrow c-kit+/Sca-1+ stem cells., PMID:20443832

Unaltered repopulation properties of mouse hematopoietic stem cells transduced with lentiviral vectors., PMID:18684860

Identification of osteo-adipo progenitor cells in fat tissue., PMID:18616697

Expression, localization and tau exon 10 splicing activity of the brain RNA-binding protein TNRC4., PMID:17725984

Non-canonical Wnt signaling enhances differentiation of Sca1+/c-kit+ adipose-derived murine stromal vascular cells into spontaneously beating cardiac myocytes., PMID:17706246

Differential effects of polyglutamine proteins on nuclear organization and artificial reporter splicing., PMID:17526020

Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1., PMID:17442486

Intranuclear immunolocalization of 14-3-3 protein isoforms in brains with spinocerebellar ataxia type 1., PMID:17224237

Antibodies to stem cell marker antigens reduce engraftment of hematopoietic stem cells., PMID:17008427

Identification of label-retaining cells in mouse endometrium., PMID:16456137

A cell-based screen for modulators of ataxin-1 phosphorylation., PMID:15757972

Proteasome function is inhibited by polyglutamine-expanded ataxin-1, the SCA1 gene product., PMID:15750336

RNA association and nucleocytoplasmic shuttling by ataxin-1., PMID:15615787

Slipped (CTG).(CAG) repeats of the myotonic dystrophy locus: surface probing with anti-DNA antibodies., PMID:12963369

Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells., PMID:12893416

Temporal patterns of bone marrow cell differentiation following transplantation in doxorubicin-induced cardiomyopathy., PMID:12757879

Phenotypic effects of expanded ataxin-1 polyglutamines with interruptions in vitro., PMID:11719269

New anti-huntingtin monoclonal antibodies: implications for huntingtin conformation and its binding proteins., PMID:11719267

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein., PMID:11001934

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice., PMID:10624951

Nuclear inclusions in spinocerebellar ataxia type 1., PMID:9928833

The expanding world of ataxins., PMID:8896544

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias., PMID:7477379

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Ataxin-1 Antibody (N76/8) [RHC51603]
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