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Anti-Gs protein, alpha subunit Antibody (N192/12)

Catalog #:   RHC43801 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHC43801

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

POLA1, POLA, DNA polymerase alpha catalytic subunit p180, DNA polymerase alpha catalytic subunit

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N192/12

Data Image
References

Protective RBD-dimer vaccines against SARS-CoV-2 and its variants produced in glycoengineered Pichia pastoris., PMID:39213280

PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells., PMID:36171284

Evaluation of autoantibody signatures in pituitary adenoma patients using human proteome arrays., PMID:35939377

Development of [211At]astatine-based anti-CD123 radioimmunotherapy for acute leukemias and other CD123+ malignancies., PMID:35474099

Efficacy and safety of guselkumab in patients with active psoriatic arthritis who are inadequate responders to tumour necrosis factor inhibitors: results through one year of a phase IIIb, randomised, controlled study (COSMOS)., PMID:34819273

Osteocytes control myeloid cell proliferation and differentiation through Gsα-dependent and -independent mechanisms., PMID:32557809

A G protein-coupled receptor mediates neuropeptide-induced oocyte maturation in the jellyfish Clytia., PMID:32126082

Analyses of the gene structure and function of olive flounder (Paralichthys olivaceus) interleukin 12 (IL-12)., PMID:31108176

Cryo-EM structures of GPCRs coupled to Gs, Gi and Go., PMID:30930094

The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance., PMID:30786811

Activation of RANK/RANKL/OPG Pathway Is Involved in the Pathophysiology of Fibrous Dysplasia and Associated With Disease Burden., PMID:30496606

Loss of Gsα in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity., PMID:30266511

Osteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots., PMID:27653320

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs., PMID:27362234

Redox proteomics identification of specifically carbonylated proteins in the hippocampi of triple transgenic Alzheimer's disease mice at its earliest pathological stage., PMID:25890254

Simultaneous visualization and cell-specific confirmation of RNA and protein in the mouse retina., PMID:25352743

Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester., PMID:25206290

Inhibition of PI3Kδ reduces kidney infiltration by macrophages and ameliorates systemic lupus in the mouse., PMID:24935930

Design, synthesis, and characterization of a 39 amino acid peptide mimic of the main immunogenic region of the Torpedo acetylcholine receptor., PMID:24491490

Increased 8-hydroxy-2'-deoxyguanosine in plasma and decreased mRNA expression of human 8-oxoguanine DNA glycosylase 1, anti-oxidant enzymes, mitochondrial biogenesis-related proteins and glycolytic enzymes in leucocytes in patients with systemic lupus erythematosus., PMID:24345202

An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer., PMID:23752180

Coupling factor 6 enhances the spontaneous microaggregation of platelets by decreasing cytosolic cAMP irrespective of antiplatelet therapy., PMID:23388886

Modification of heterotrimeric G-proteins in Swiss 3T3 cells stimulated with Pasteurella multocida toxin., PMID:23144805

Denosumab treatment for fibrous dysplasia., PMID:22431375

Interaction of relaxin-like gonad-stimulating substance with ovarian follicle cells of the starfish Asterina pectinifera., PMID:21967225

[Metabolic characteristics of GS-nS0 myeloma cells producing anti-CD25 monoclonal antibody in serum-free culture]., PMID:19835150

Evaluation of alpha-tubulin as an antigenic and molecular probe to detect Giardia lamblia., PMID:19724704

Extralarge XL(alpha)s (XXL(alpha)s), a variant of stimulatory G protein alpha-subunit (Gs(alpha)), is a distinct, membrane-anchored GNAS product that can mimic Gs(alpha)., PMID:19423757

Regulation of spermatogenesis in McCune-Albright syndrome: lessons from a 15-year follow-up., PMID:18505910

Fusion of hC3d3 to hCGbeta enhances responsiveness in vitro of human peripheral immunocompetent cells upon the antigen primary challenge., PMID:18479753

Regulation of caveolar cardiac sodium current by a single Gsalpha histidine residue., PMID:18281377

[Atypical clinical presentation of pseudohypoparathyroidism coexisting with autoimmune disorders]., PMID:18058726

Meiotic resumption of porcine immature oocytes is prevented by ooplasmic Gsalpha functions., PMID:17693700

Glucosamine sulfate inhibits TNF-alpha and IFN-gamma-induced production of ICAM-1 in human retinal pigment epithelial cells in vitro., PMID:16431966

Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi., PMID:16415502

Effect of parenteral vitamin E and selenium supplementation on immune status of dogs vaccinated with subunit and somatic antigens against Taenia hydatigena., PMID:16083066

Copper and zinc inhibit Galphas function: a nucleotide-free state of Galphas induced by Cu2+ and Zn2+., PMID:15546818

[Recent data on the physiopathology of hyperthyroidism]., PMID:14556475

Alkylation of sulfhydryl groups on Galpha(s/olf) subunits by N-ethylmaleimide: regulation by guanine nucleotides., PMID:12832082

Effects of G-protein-specific antibodies and G beta gamma subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells., PMID:12788820

Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase., PMID:12708755

Somatostatin receptors (sst2) are coupled to Go and modulate GTPase activity in the rabbit retina., PMID:12562507

Differential expression of the adenylyl cyclase-stimulatory guanosine triphosphate-binding protein G(s)alpha in the human myometrium during pregnancy and labor involves transcriptional regulation by cyclic adenosine 3',5'-monophosphate and binding of phosphorylated nuclear proteins to multiple GC boxes within the promoter., PMID:12466371

Genetic characterization of growth hormone deficiency and resistance: implications for treatment with recombinant growth hormone., PMID:12083945

Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude., PMID:11884374

Opposing changes of trimeric G protein levels during ontogenetic development of rat brain., PMID:11850064

Clonal composition of human adamantinomatous craniopharyngiomas and somatic mutation analyses of the patched (PTCH), Gsalpha and Gi2alpha genes., PMID:11524144

Somatotropin has no effect on the quantity of guanine nucleotide binding proteins Gqalpha/G11alpha in goat adipose tissue in vivo., PMID:11252533

Expression of the extra-large G protein alpha-subunit XLalphas in neuroepithelial cells and young neurons during development of the rat nervous system., PMID:11248437

Co-localization of receptor and transducer proteins in the glycosphingolipid-enriched, low density, detergent-insoluble membrane fraction of sea urchin sperm., PMID:11201792

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Gs protein, alpha subunit Antibody (N192/12) [RHC43801]
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