Catalog No.
RHA99302
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
BCNG-1, BCNG1, HCN1, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, Brain cyclic nucleotide-gated channel 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N70/28
Adrenomedullin-mediated depressor response with visceral afferent-specific membrane depolarization in isolated nodose ganglion neurons from adult female rat., PMID:39427564
Ion channel profiles of extraocular motoneurons and internuclear neurons in human abducens and trochlear nuclei., PMID:38957435
Identification of novel pulmonary vein nodes as generators of ectopic arrhythmic foci for atrial fibrillation: an immunohistochemical proof., PMID:34994828
Expression of the pacemaker channel HCN4 in excitatory interneurons in the dorsal horn of the murine spinal cord., PMID:32948209
Localization of Retinal Ca2+/Calmodulin-Dependent Kinase II-β (CaMKII-β) at Bipolar Cell Gap Junctions and Cross-Reactivity of a Monoclonal Anti-CaMKII-β Antibody With Connexin36., PMID:31555090
HCN3 ion channels: roles in sensory neuronal excitability and pain., PMID:31290157
Expression and cellular localization of HCN channels in rat cerebellar granule neurons., PMID:27569278
Structural Changes and Lack of HCN1 Channels in the Binaural Auditory Brainstem of the Naked Mole-Rat (Heterocephalus glaber)., PMID:26760498
Organ of Corti explants direct tonotopically graded morphology of spiral ganglion neurons in vitro., PMID:26663318
Decreased expression of hyperpolarisation-activated cyclic nucleotide-gated channel 3 in Hirschsprung's disease., PMID:25987789
Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart., PMID:21945247
Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells., PMID:21456027
Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice., PMID:20140458
Hyperpolarization-activated cyclic-nucleotide gated 4 (HCN4) protein is expressed in a subset of rat dorsal root and trigeminal ganglion neurons., PMID:19820968
Diabetes alters protein expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits in rat nodose ganglion cells., PMID:19815055
Involvement of hyperpolarization-activated, cyclic nucleotide-gated cation channels in dorsal root ganglion in neuropathic pain., PMID:18958363
Hyperpolarization-activated cyclic nucleotide-gated channel mRNA and protein expression in large versus small diameter dorsal root ganglion neurons: correlation with hyperpolarization-activated current gating., PMID:18450385
In the ventral cochlear nucleus Kv1.1 and subunits of HCN1 are colocalized at surfaces of neurons that have low-voltage-activated and hyperpolarization-activated conductances., PMID:18424000
A subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels., PMID:18218331
A hyperpolarization-activated, cyclic nucleotide-gated, (Ih-like) cationic current and HCN gene expression in renal inner medullary collecting duct cells., PMID:18199706
Activity-dependent regulation of h channel distribution in hippocampal CA1 pyramidal neurons., PMID:17848552
Expression of hyperpolarization-activated cyclic nucleotide-gated cation channels in rat dorsal root ganglion neurons innervating urinary bladder., PMID:16979600
Hyperpolarization-activated cation channels are expressed in rat hypothalamic gonadotropin-releasing hormone (GnRH) neurons and immortalized GnRH neurons., PMID:16879992
The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides., PMID:15923185
Distribution of HCN1 and HCN2 in rat auditory brainstem nuclei., PMID:15245481
Hyperpolarization-activated, cyclic nucleotide-gated cation channels: roles in the differential electrophysiological properties of rat primary afferent neurons., PMID:15139030
Bidirectional interactions between h-channels and Na+-K+ pumps in mesencephalic trigeminal neurons., PMID:15071118
Characterisation of hyperpolarization-activated currents (I(h)) in the medial septum/diagonal band complex in the mouse., PMID:15047026
HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals., PMID:12786975
Carbohydrates engineered at antibody constant domains can be used for site-specific conjugation of drugs and chelates., PMID:9692846
Structure determination of N-linked oligosaccharides engineered at the CH1 domain of humanized LL2., PMID:9376682
Rapid neurite formation in a human cortical neuronal cell line., PMID:8779309
Human cortical neuronal cell line (HCN-1): further in vitro characterization and suitability for brain transplantation., PMID:1344290
Induction of ICAM-1 on human neural cells and mechanisms of neutrophil-mediated injury., PMID:1684266
For research use only. Not for human or drug use.
