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Anti-Parkin Antibody (N136/16)

Catalog #:   RHA85301 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHA85301

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Parkin, PARK2, Parkinson juvenile disease protein 2, E3 ubiquitin-protein ligase parkin, Parkin RBR E3 ubiquitin-protein ligase, PRKN, Parkinson disease protein 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N136/16

Data Image
References

Molnupiravir or nirmatrelvir-ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial., PMID:40383127

Repurposing chlorpromazine for the treatment of triple-negative breast cancer growth and metastasis based on modulation of mitochondria-mediated apoptosis and autophagy/mitophagy., PMID:40217096

Effect of Bacille Calmette-Guérin vaccination on immune responses to SARS-CoV-2 and COVID-19 vaccination., PMID:39872402

PACRG is Expressed on the Left Side of the Brain Vesicle in the Ascidian Halocynthia Larva., PMID:39845515

SQYC formula improves the efficacy of PD-1 monoclonal antibodies in MSS colorectal cancer by regulating dendritic cell mitophagy via the PINK1-Parkin pathway., PMID:39826284

Ara h 2-expressing cucumber mosaic virus-like particle (VLP Peanut) induces in vitro tolerogenic cellular responses in peanut-allergic individuals., PMID:39756833

The TLR7/8 agonist INI-4001 enhances the immunogenicity of a Powassan virus-like-particle vaccine., PMID:39677812

An Inducible Luminescent System to Explore Parkinson's Disease-Associated Genes., PMID:39273438

Protective effects of Parkin knockout on asthma-induced changes in juvenile mice: inflammation, airway resistance, and oxidative stress., PMID:39269783

Belantamab mafodotin, pomalidomide, and dexamethasone for triple class exposed/refractory relapsed multiple myeloma: a subgroup analysis of the ALGONQUIN trial., PMID:39261451

Early warning COVID-19 outbreak in long-term care facilities using wastewater surveillance: correlation, prediction, and interaction with clinical and serological statuses., PMID:39182502

Seroprevalence of SARS-CoV-2 antibodies among children receiving primary care in Toronto, Ontario., PMID:39168962

Zn0-Induced Cytotoxicity and Mitochondrial Stress in Microglia: Implications of the Protective Role of Immunoglobulin G In Vitro., PMID:39129512

Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles., PMID:38989951

Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes., PMID:38987265

Kinetics of SARS-CoV-2 infection biomarkers in a household transmission study., PMID:38811590

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue., PMID:38802071

Astragaloside IV protects against autoimmune myasthenia gravis in rats via regulation of mitophagy and apoptosis., PMID:38785143

Specific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines-an exploratory sub-study of the BRACE trial., PMID:38663355

Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis., PMID:38574977

Quadriceps muscle atrophy after non-invasive anterior cruciate ligament injury: evidence linking to autophagy and mitophagy., PMID:38496299

'Omalizumab changed my life': a patient perspective on solar urticaria., PMID:38491908

Nasal allergen-neutralizing antibodies correlate closely with tolerated intranasal allergen challenge dose following grass pollen subcutaneous immunotherapy in patients with local allergic rhinitis., PMID:38483174

GRAF1 Acts as a Downstream Mediator of Parkin to Regulate Mitophagy in Cardiomyocytes., PMID:38474413

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue., PMID:38293125

Comparative analysis of primate and pig cells reveals primate-specific PINK1 expression and phosphorylation., PMID:38287905

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial., PMID:38272046

Belantamab mafodotin, pomalidomide and dexamethasone in refractory multiple myeloma: a phase 1/2 trial., PMID:38177852

HMGB1-RAGE axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte autophagy and apoptosis in diabetic mice., PMID:37768929

[Effect of acupotomy on mitophagy mediated by PINK1/Parkin pathway in cartilage of rabbits with knee osteoarthritis]., PMID:37730260

Parkinson's disease neurons exhibit alterations in mitochondrial quality control proteins., PMID:37553379

β-Lapachone Exerts Anticancer Effects by Downregulating p53, Lys-Acetylated Proteins, TrkA, p38 MAPK, SOD1, Caspase-2, CD44 and NPM in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells., PMID:37373014

The protective effects of Bacillus licheniformis against inflammatory responses and intestinal barrier damage in broilers with necrotic enteritis induced by Clostridium perfringens., PMID:37309567

Redefining Autoimmune Disorders' Pathoetiology: Implications for Mood and Psychotic Disorders' Association with Neurodegenerative and Classical Autoimmune Disorders., PMID:37174637

Single-cell RNA sequencing identifies precise tolerogenic cellular and molecular pathways induced by depigmented-polymerized grass pollen allergen extract., PMID:36649758

Rapamycin regulates osteogenic differentiation through Parkin-mediated mitophagy in rheumatoid arthritis., PMID:36379150

Resveratrol Protects against Zearalenone-Induced Mitochondrial Defects during Porcine Oocyte Maturation via PINK1/Parkin-Mediated Mitophagy., PMID:36136579

Inflammatory diseases in hematology: a review., PMID:35938681

Vaccine-induced prothrombotic immune thrombocytopenia without thrombosis may not require immune modulatory therapy: A case report., PMID:35599706

Clinical care pathway for the evaluation of patients with suspected VITT after ChAdOx1 nCoV-19 vaccination., PMID:35201292

BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα., PMID:35180123

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial., PMID:35151397

Mammalian Cell-Free System Recapitulates the Early Events of Post-Fertilization Sperm Mitophagy., PMID:34572103

Potential of PINK1 and PARKIN Proteins as Biomarkers for Active Multiple Sclerosis: A Japanese Cohort Study., PMID:34421896

Preparation and characterization of a polyclonal antibody against PTEN-Long., PMID:34338347

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial., PMID:34000257

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial., PMID:33933206

Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteins during mitophagy., PMID:33872670

Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy., PMID:33819508

Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites., PMID:33694021

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Parkin Antibody (N136/16) [RHA85301]
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