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Anti-Synaptotagmin-5 Antibody (N274/8)

Catalog #:   RHA11903 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHA11903

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

SytV, SYT5, Synaptotagmin-5, Synaptotagmin V

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N274/8

Data Image
References

PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exocytosis and endocytosis., PMID:40128278

Repetitive transcranial magnetic stimulation alleviates motor impairment in Parkinson's disease: association with peripheral inflammatory regulatory T-cells and SYT6., PMID:39456006

Autoantibodies towards HFE and SYT5 in anti-neutrophil cytoplasm antibody-associated vasculitis relapse., PMID:39400561

A guide to selecting high-performing antibodies for Synaptotagmin-1 (Uniprot ID P21579) for use in western blot, immunoprecipitation, immunofluorescence and flow cytometry., PMID:39169954

Non-canonical function of ADAM10 in presynaptic plasticity., PMID:39123091

Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1., PMID:38758649

Identifying biomarkers deciphering sepsis from trauma-induced sterile inflammation and trauma-induced sepsis., PMID:38283341

Simulations of active zone structure and function at mammalian NMJs predict that loss of calcium channels alone is not sufficient to replicate LEMS effects., PMID:37073966

Extended-synaptotagmin 1 engages in unconventional protein secretion mediated via SEC22B+ vesicle pathway in liver cancer., PMID:36044553

Synaptotagmins 1 and 7 Play Complementary Roles in Somatodendritic Dopamine Release., PMID:35361702

The Effect of TGF-β1 Reduced Functionality on the Expression of Selected Synaptic Proteins and Electrophysiological Parameters: Implications of Changes Observed in Acute Hepatic Encephalopathy., PMID:35163004

Plasma Membrane Receptors Involved in the Binding and Response of Osteoclasts to Noncellular Components of the Bone., PMID:34576260

Unique dynamics and exocytosis properties of GABAergic synaptic vesicles revealed by three-dimensional single vesicle tracking., PMID:33622785

Interactions of Antibodies to the Gram-Negative Gastric Bacterium Helicobacter pylori with the Synaptic Calcium Sensor Synaptotagmin 5, Correlate to Impaired Vesicle Recycling in SiMa Human Neuroblastoma Cells., PMID:32860155

Increased urinary exosomal SYT17 levels in chronic active antibody-mediated rejection after kidney transplantation via the IL-6 amplifier., PMID:32369831

Synaptotagmin 1 Is Involved in Neuropathic Pain and Electroacupuncture-Mediated Analgesic Effect., PMID:32024024

Growth Hormone-Releasing Hormone Modulation of Neuronal Exosome Biomarkers in Mild Cognitive Impairment., PMID:30372675

Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis., PMID:30038018

Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation., PMID:29206031

Arabidopsis SYT1 maintains stability of cortical endoplasmic reticulum networks and VAP27-1-enriched endoplasmic reticulum-plasma membrane contact sites., PMID:27811083

In vitro potency determination of botulinum neurotoxin B based on its receptor-binding and proteolytic characteristics., PMID:27032463

Presynaptic protein Synaptotagmin1 regulates the neuronal polarity and axon differentiation in cultured hippocampal neurons., PMID:26667128

Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1., PMID:26400647

Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair., PMID:25143396

Global analysis of S-nitrosylation sites in the wild type (APP) transgenic mouse brain-clues for synaptic pathology., PMID:24895380

Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release., PMID:24267651

Up-regulation of Synaptotagmin IV within amyloid plaque-associated dystrophic neurons in Tg2576 mouse model of Alzheimer's disease., PMID:24170720

Synaptotagmin 1 is required for vesicular Ca²⁺/H⁺-antiport activity., PMID:23607712

Characterization of small-field bistratified amacrine cells in macaque retina labeled by antibodies against synaptotagmin-2., PMID:22821706

Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells., PMID:22820376

Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron., PMID:22778403

Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen., PMID:22398727

Subcellular localization and putative role of VPS13A/chorein in dopaminergic neuronal cells., PMID:22366033

Expression, localization, and functional role for synaptotagmins in pancreatic acinar cells., PMID:21636530

Dissociation of inositol polyphosphates from the C2B domain of synaptotagmin facilitates spontaneous release of catecholamines in adrenal chromaffin cells. A suggestive evidence of a fusion clamp by synaptotagmin., PMID:21402086

Extended-synaptotagmin-2 mediates FGF receptor endocytosis and ERK activation in vivo., PMID:20833364

Neurites from PC12 cells are connected to each other by synapse-like structures., PMID:20698031

A new neutralizing antibody against botulinum neurotoxin B recognizes the protein receptor binding sites for synaptotagmins II., PMID:20650331

Calcineurin-mediated dephosphorylation of synaptotagmin VI is necessary for acrosomal exocytosis., PMID:20551332

[Lambert-Eaton myasthenic syndrome (LEMS)]., PMID:20420183

Limited intermixing of synaptic vesicle components upon vesicle recycling., PMID:20230528

Selective perturbation of the BAR domain of endophilin impairs synaptic vesicle endocytosis., PMID:20222153

p35 is required for CDK5 activation in cellular senescence., PMID:20181942

Production and characterization of a recombinant chimeric antigen consisting botulinum neurotoxin serotypes A, B and E binding subdomains., PMID:20118620

Cholesterol reduction impairs exocytosis of synaptic vesicles., PMID:20103534

Recombinant luminal domain of human synaptotagmin II in combination with gangliosides inhibits the toxicity of botulinum neurotoxins in mice., PMID:20080203

EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain., PMID:20067584

[Participation of synaptotagmin in release of catecholamines in rat adrenal chromaffin cells]., PMID:21469315

[Recent advance in research for myasthenia gravis, in relation to various antibodies affecting synaptic structure and function]., PMID:20030211

Nitric oxide and cyclic nucleotide signal transduction modulates synaptic vesicle turnover in human model neurons., PMID:19807845

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Synaptotagmin-5 Antibody (N274/8) [RHA11903]
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