Serclutamab talirine (ADC)

Catalog No.

DHB86999

Description

Serclutamab talirine is an ADC consisting of an EGFR-directed antibody and PBD used for the study of several solid tumors.

Species reactivity

Human

Clonality

Monoclonal

Target

EGFR

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SEC.

Purification

Purified by Ion Exchange Chromatography.

Applications

Research Grade Biosimilar

Form

Liquid

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ABBV-321

Clone ID

Serclutamab talirine

Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma., PMID:36814898

Convection enhanced delivery of EGFR targeting antibody-drug conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts., PMID:36071925

Targeting Multiple EGFR-expressing Tumors with a Highly Potent Tumor-selective Antibody-Drug Conjugate., PMID:32847977

Document Download

Serclutamab talirine (ADC).pdf